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journal article·2025-05Open access

Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism (Adv. Sci. 19/2025)

Mathilde Gagliardini, Sabrina Mechaussier, Carolina Campos Pina, Monica Morais, Olivier Postal, Philippe Jean, Typhaine Dupont, Amrit Singh‐Estivalet, Shéhanie Udugampolage, Cyril Scandola, Elisabeth Verpy, Baptiste Libé‐Philippot, Talya C. Inbar, Joanna Schwenkgrub, Carla Maria Barbosa Spinola, Raphaël Etournay, Aziz El‐Amraoui, Brice Bathellier, Adeline Mallet, Sedigheh Delmaghani, Fabrice Giraudet, Christine Petit, Boris Gourévitch, Paul Avan, Nicolas Michalski

Advanced Science· Volume 12· Issue 19
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Source abstract

Abstract

Auditory Neuropathy Mechanism The frontispiece refers to the peripheral auditory system with its exiting neurons of the auditory nerve. The rainbow appearance of the auditory nerve neurons represents the different sub-circuits suggested by the results of the study. The audio equalizer points to the relative contribution of these circuits and is reminiscent of a DNA gel reminding the genetic nature of the auditory neuropathy described. More details can be found in article number 2410776 by Nicolas Michalski and co-workers. Image credits: Sabrina Mechaussier.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Hearing, Cochlea, Tinnitus, Genetics · Biochemical Analysis and Sensing Techniques

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