journal article·2025-05Open access

High‐Viability Circulating Tumor Cells Sorting From Whole Blood at Single Cell Level Using Laser‐Induced Forward Transfer‐Assisted Microfiltration (Adv. Sci. 18/2025)

Qingmei Xu, Yuntong Wang, Songtao Dou, Yang Xu, Zhenhe Xu, Han Xu, Yi Zhang, Yanming Xia, Ying Xue, Hang Li, Xiao Ma, Kunlong Zhang, Huan Wang, Fengzhou Ma, Qi Wang, Bei Li, Wei Wang

Advanced Science· Volume 12· Issue 18

Abstract

Integrated Single Rare Cell Sorting System Circulating tumor cells (CTCs) represent a rare and heterogeneous population of cancer cells, serving as critical biomarkers for metastasis monitoring and personalized medicine. However, efficiently isolating single, high-viability CTCs from complex blood environments remains a significant challenge. In article 2414195, Wei Wang, Bei Li, Qi Wang, and co-workers present a laser-induced forward transfer-assisted microfiltration system for the high-efficiency enrichment and precise retrieval of single CTCs from whole blood. This innovative platform provides a robust and versatile tool for advancing single-CTC research.
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Research context

OpenAlex topics: Cancer Cells and Metastasis · Microfluidic and Bio-sensing Technologies

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