Thermally Triggered Double Emulsion‐Integrated Hydrogel Microparticles for Multiplexed Molecular Diagnostics (Adv. Sci. 12/2025)

Double Emulsion-Integrated Hydrogel Microparticles In article number 2408158, Sang Kyung Kim, Seungwon Jung, and co-workers introduce TaqPIN, a hydrogel microparticle platform for multiplexed molecular diagnostics. Thermo-responsive double emulsion carriers efficiently deliver target-specific reagents into each microparticle, where confined amplification enables independent reactions. Integrated into a structured array, TaqPIN achieves nine-plex SARS-CoV-2 variant detection with high sensitivity and specificity.