Hybrid Cell Membrane‐Engineered Nanocarrier for Triple‐Action Strategy to Address Pseudomonas aeruginosa Infection (Adv. Sci. 6/2025)

Hybrid Cell Membrane-Engineered Nanocarrier In article number 2411261 by Mi Zhou, Xiaoxiao Cai, and co-workers, a hybrid cell membraneengineered nanocarrier called TTob@NPM is developed to address recalcitrant Pseudomonas aeruginosa lung infection with three mechanisms: inflammation targeting, bacteria killing, and immunomodulation, representing a potent antibiotic delivery system with both simplicity and efficacy. This is analogous to the traditional Chinese story of “Monkey Hit White-Skeleton Demon Thrice”. White-Skeleton Demon changes herself into three different forms while Monkey sees through all her disguises and finally subdues her.