A Study on the Inflammatory Response of the Brain in Neurosyphilis (Adv. Sci. 5/2025)
Source abstract
Abstract
Neurosyphilis In article number 2406971, Ling Leng, Jun Li, and co-workers reveal the mechanisms of inflammation and immune-mediated brain injury in patients with Neurosyphilis. By combination of proteomic and scRNA sequencing analysis, researchers identified Toll-like/NF-κB signaling as the key pathway involved in central nervous system damage in Neurosyphilis and further verified the damaging effects of peripheral inflammatory cells on the brain using organoids.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Syphilis Diagnosis and Treatment · Reproductive System and Pregnancy
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