journal article·2025-02Open access

Resensitizing β‐Lactams by Reprogramming Purine Metabolism in Small Colony Variant for Osteomyelitis Treatment (Adv. Sci. 5/2025)

Tingwang Shi, Qiong Wu, Zesong Ruan, Zhiyuan Luo, Wenbo Wang, Zhao Guo, Yihong Ma, Xin Wang, Guangyu Chu, Han Lin, Min Ge, Yunfeng Chen

Advanced Science· Volume 12· Issue 5

Abstract

Small Colony Variant The phenotypic instability of small colony variants (SCVs) complicates investigating their role in osteomyelitis. Min Ge, Yunfeng Chen, and co-workers clarified the pathogenic mechanism of clinically isolated SCVs with hpt mutations and proposed a nanomedicine system for co-delivering antibiotics to treat SCV-associated osteomyelitis. More details are available in article number 202410781.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Orthopedic Infections and Treatments · Blood disorders and treatments · Pneumocystis jirovecii pneumonia detection and treatment

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References

Reference metadata was not supplied for this record.