journal article·2025-01Open access

Efficient Predictor for Immunotherapy Efficacy: Detecting Pan‐Clones Effector Tumor Antigen‐Specific T Cells in Blood by Nanoparticles Loading Whole Tumor Antigens (Adv. Sci. 2/2025)

Weibiao Zeng, Jin Wang, Zhike Chen, Jian Yang, Ao Zhu, Yan Zheng, Xianlan Chen, Yuhan Liu, Leilei Wu, Yufeng Xie, Sheng Ju, Jun Chen, Cheng Ding, Chang Li, Xin Tong, Mi Liu, Jun Zhao

Advanced Science· Volume 12· Issue 2

Abstract

Efficient Predictor for Immunotherapy Efficacy In article number 2409913, Xin Tong, Mi Liu, Jun Zhao, and co-workers present a new biomarker to predict therapeutic efficacy: detecting the amount of effector tumor antigen-specific T cells (ETASTs) in peripheral blood of cancer patients. ETATSs increase in blood of cancer patient that are responsive to immunotherapy, but not increase in blood of non-responders.
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Research context

OpenAlex topics: Immunotherapy and Immune Responses · Monoclonal and Polyclonal Antibodies Research · vaccines and immunoinformatics approaches

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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