Bmi‐1 Epigenetically Orchestrates Osteogenic and Adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells to Delay Bone Aging (Adv. Sci. 46/2024)

Jingyu Zhao; Ao Chen; Rong Wang; Dong Qiu; Haiyun Chen; Jiyu Li; Jin'ge Zhang; Tianxiao Wang; Yue Wang; Yujie Lin; Jiawen Zhou; Yifei Du; Hua Yuan; Yongjie Zhang; Dengshun Miao; Yuli Wang; Jianliang Jin

doi:10.1002/advs.202470284

journal article·2024-12Open access

Bmi‐1 Epigenetically Orchestrates Osteogenic and Adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells to Delay Bone Aging (Adv. Sci. 46/2024)

Jingyu Zhao, Ao Chen, Rong Wang, Dong Qiu, Haiyun Chen, Jiyu Li, Jin'ge Zhang, Tianxiao Wang, Yue Wang, Yujie Lin, Jiawen Zhou, Yifei Du, Hua Yuan, Yongjie Zhang, Dengshun Miao, Yuli Wang, Jianliang Jin

Advanced Science· Volume 11· Issue 46

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Source abstract

Abstract

Bone Marrow Mesenchymal Stem Cells Jianliang Jin, Yuli Wang, and co-workers discovered Bmi-1 epigenetically modulates osteogenic and adipogenic differentiation of bone-marrow mesenchymal stem cells (BMSCs), crucial for senile osteoporosis prevention. The image creatively depicts BMSCs as workers with “Bmi-1” helmets forming bone, with flags signifying osteoblast differentiation. “Prx1” drones deliver “Bmi-1”-labeled helmets, highlighting Bmi-1's role in BMSCs osteogenic differentiation. More details can be found in article number 2404518. Art by Lijuan Zong, Ying Tao and Cheng Qian.

Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Mesenchymal stem cell research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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