journal article·2024-04Open access

Injectable and Self‐Curing Single‐Component Hydrogel for Stem Cell Encapsulation and In Vivo Bone Regeneration (Adv. Sci. 16/2024)

Seo Young Cheon, Ji Sun Park, Yeeun Lee, Chaehyun Lee, Hayoung Jeon, Donghyun Lee, Se Hee Kim, Seong Gi Lim, Heebeom Koo

Advanced Science· Volume 11· Issue 16

Abstract

Injectable Hydrogel Heebeom Koo and co-workers developed an injectable, single-component hydrogel with hyaluronic acid modified with phenylboronic acid and spermidine. It has a shear-thinning property, enabling its injection through a syringe to form a stable hydrogel inside the body. In addition, the hydrogel undergoes a post-injection ‘self-curing’, which stiffens the hydrogel over time. Therefore, the hydrogel meets the physical requirements for stem cell therapy in rigid tissues, such as bone, while maintaining injectability. More details can be found in article number 2304861.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research

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