journal article·2022-05Open access

Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities (Adv. Sci. 16/2022)

Luwen Zhang, Qiong Zhao, Hui Cang, Ziqiang Wang, Xiaojia Hu, Ruolang Pan, Yang Yang, Ye Chen

Advanced Science· Volume 9· Issue 16

Abstract

Acute Myeloid Leukemia In article number 2105811, Yang Yang, Ye Chen, and co‐workers report that acute myeloid leukemia (AML) cells educate regular mesenchymal stromal cells (MSCs) towards an adipogenic differentiation propensity with leukemia promotion capabilities. The fish's gradient colors symbolize the influence of the leukemia cells (in black) and hematopoietic stem cells (in red) on their respective surrounding microenvironments. [Image: see text]
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Research context

OpenAlex topics: Mesenchymal stem cell research

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