DataVXAdvanced SciencePaper
journal article·2022-02Open access

Pressure Drives Rapid Burst‐Like Coordinated Cellular Motion from 3D Cancer Aggregates (Adv. Sci. 6/2022)

Swetha Raghuraman, Ann‐Sophie Schubert, Stephan Bröker, Alejandro Jurado, Annika Müller, Matthias Brandt, Bart E. Vos, Arne D. Hofemeier, Fatemeh Abbasi, Martin Stehling, Raphael Wittkowski, Johanna Ivaska, Timo Betz

Advanced Science· Volume 9· Issue 6
Publisher pageOpen full text
Source abstract

Abstract

Coordinated Cell Motion In article number 2104808 by Swetha Raghuraman, Timo Betz, and co-workers, a novel migration phenomenon is presented wherein cancer cells burst out from tumor aggregates as an act of pressure release into the surrounding in-homogeneous soft extra-cellular matrix (ECM) made up of collagen. The pressure within tumor aggregates manifests due to cellular swelling, leading to a super-diffusive coordinated expulsion of cells within 12 hours, directed towards regions providing least mechanical resistance
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: 3D Printing in Biomedical Research · Cellular Mechanics and Interactions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References

Reference metadata was not supplied for this record.