journal article·2021-10Open access

Erythrocytes, a New Contributor to Age‐Associated Loss of Blood–Brain Barrier Integrity (Adv. Sci. 20/2021)

Payam Amiri, Jonalyn DeCastro, Joshua Littig, Hsiang‐Wei Lu, Chao Liu, Irina Conboy, Kiana Aran

Advanced Science· Volume 8· Issue 20

Abstract

Blood–Brain Barriers In article number 2101912, Irina Conboy, Kiana Aran, and co‐workers show that erythrocytes derived from old mammals (mice and people) have deleterious effects on the integrity of the blood‐brain barrier, when compared to the young donor cells. This previously unknown change in erythrocyte behavior unveils a new mechanism of age‐associated neurological decline. Image credits: Ella Maru Studio. [Image: see text]
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Erythrocyte Function and Pathophysiology

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