journal article·2020-12Open access

SARS‐CoV‐2: Bioinspired DNase‐I‐Coated Melanin‐Like Nanospheres for Modulation of Infection‐Associated NETosis Dysregulation (Adv. Sci. 23/2020)

Hee Ho Park, Wooram Park, Yun Young Lee, Hyelim Kim, Hee Seung Seo, Dong Wook Choi, Ho‐Keun Kwon, Dong Hee Na, Tae‐Hyung Kim, Young Bin Choy, June Hong Ahn, Wonhwa Lee, Chun Gwon Park

Advanced Science· Volume 7· Issue 23

Abstract

In article number 2001940, June Hong Ahn, Wonhwa Lee, Chun Gwon Park, and co‐workers demonstrate that NETosis factor can be a potential therapeutic target for the treatment of SARS‐CoV‐2‐induced sepsis. DNase‐I coated melanin‐like nanospheres (DNase‐I pMNSs) show excellent stability, modulation of sepsis‐associated NETosis dysregulation and prevention of further disease progression. [Image: see text]
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Neutrophil, Myeloperoxidase and Oxidative Mechanisms · Advanced Nanomaterials in Catalysis · Medical and Biological Ozone Research

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