journal article·2020-09Open access

Nanomedicine: A Nanomedicine Fabricated from Gold Nanoparticles‐Decorated Metal–Organic Framework for Cascade Chemo/Chemodynamic Cancer Therapy (Adv. Sci. 17/2020)

Yuan Ding, Hao Xu, Chang Xu, Zongrui Tong, Sitong Zhang, Yang Bai, Yining Chen, Qianhui Xu, Liuzhi Zhou, Hao Ding, Zhongquan Sun, Sheng Yan, Zhengwei Mao, Weilin Wang

Advanced Science· Volume 7· Issue 17

Abstract

In article number 2001060, Sheng Yan, Zhengwei Mao, Weilin Wang, and co‐workers fabricate a hybrid nanomedicine (Au/FeMOF@CPT NPs) using metal–organic framework (MOF) nanoparticles and gold nanoparticles (Au NPs) as building blocks. The intracellular glucose can be oxidized by Au NPs to produce hydrogen dioxide, which is further utilized as chemical fuel for the Fenton reaction, thus realizing the synergistic anticancer efficacy. [Image: see text]
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Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanoplatforms for cancer theranostics · Metal-Organic Frameworks: Synthesis and Applications

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