DataVXAdvanced SciencePaper
journal article·2020-04Open access

Cardiac Cavity Tracking: CACCT: An Automated Tool of Detecting Complicated Cardiac Malformations in Mouse Models (Adv. Sci. 8/2020)

Qing Chu, Haobin Jiang, Libo Zhang, Dekun Zhu, Qianqian Yin, Hao Zhang, Bin Zhou, Wenzhang Zhou, Zhang Yue, Hong Lian, Lihui Liu, Yu Nie, Shengshou Hu

Advanced Science· Volume 7· Issue 8
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Source abstract

Abstract

In article number 1903592, Yu Nie, Shengshou Hu, and co-workers establish an automated tool based on micro-computed tomography (CT) images known as CACCT to identify complicated cardiac malformations in mice. With CACCT, researchers, even those without expert training or diagnostic experience of congenital heart diseases, can identify murine complicated cardiac malformations effectively, including transposition of the great arteries, double-outlet right ventricle and atypical ventricular septal defect, whose accuracy is equivalent to senior fetal cardiologists.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Congenital Heart Disease Studies

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Affiliations

State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Disease Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

State Key Laboratory of Computer Science Institute of Software Chinese Academy of Sciences Beijing 100089 China

Heart Center and Shanghai Institution of Pediatric Congenital Heart Diseases Shanghai Children's Medical Center National Children's Medical Center Shanghai Jiao Tong University School of Medicine Shanghai 200127 China

State Key Laboratory of Cell Biology CAS Center for Excellence in Molecular Cell Science Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences (CAS) University of Chinese Academy of Sciences Shanghai 200031 China

Department of Cardiovascular Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

References

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