journal article·2019-02Open access

Biohybrid Circuits: Biofunctionalized Materials Featuring Feedforward and Feedback Circuits Exemplified by the Detection of Botulinum Toxin A (Adv. Sci. 4/2019)

Hanna J. Wagner, Svenja Kemmer, Raphael Engesser, Jens Timmer, Wilfried Weber

Advanced Science· Volume 6· Issue 4

Abstract

In article number 1801320, Wilfried Weber and co-workers present the incorporation of biological circuits into polymer materials capable of sensing and processing an input stimulus and producing a quantitative output. Positive feedback and/or feedforward network topologies detect the proteolytic activity of botulinum toxin A with adjustable kinetics and dynamic range. Image credit: Jo Richers (www.jorichers.com).
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Botulinum Toxin and Related Neurological Disorders

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Affiliations

Faculty of Biology University of Freiburg Schänzlestraße 1 79104 Freiburg Germany

BIOSS—Centre for Biological Signalling Studies University of Freiburg Schänzlestraße 18 79104 Freiburg Germany

Spemann Graduate School of Biology and Medicine (SGBM) University of Freiburg Albertstraße 19a 79104 Freiburg Germany

Institute of Physics University of Freiburg Hermann‐Herder Straße 3 79104 Freiburg Germany

References

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