DataVXAdvanced SciencePaper
journal article·2019-01Open access

Breast Cancer Diagnosis: Cascade Reaction in Human Live Tissue Allows Clinically Applicable Diagnosis of Breast Cancer Morphology (Adv. Sci. 2/2019)

Tomonori Tanei, Ambara R. Pradipta, Koji Morimoto, Motoko Fujii, Mayumi Arata, Akihiro Ito, Minoru Yoshida, Elena Saigitbatalova, Almira Kurbangalieva, Jun‐ichiro Ikeda, Eiichi Morii, Shinzaburo Noguchi, Katsunori Tanaka

Advanced Science· Volume 6· Issue 2
Publisher pageOpen full text
Source abstract

Abstract

In article number 1801479, Shinzaburo Noguchi, Katsunori Tanaka, and co-workers use a click-to-sense probe to detect acrolein, which is universally produced by cancer cells under oxidative stress, within five minutes at room temperature. All cancer types tested are imaged and discriminated through multiple cascade reactions in the living tissue of human patients. This probe can be used to quickly and accurately diagnose cancer morphology during breast-conserving surgery, by reforming the conventional pathological methods.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Chemical Sensor Technologies · Photodynamic Therapy Research Studies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Breast and Endocrine Surgery Graduate School of Medicine Osaka University 2‐2‐E10 Yamadaoka Suita Osaka 565‐0871 Japan

Biofunctional Synthetic Chemistry Laboratory RIKEN Cluster for Pioneering Research 2‐1 Hirosawa Wako Saitama 351‐0198 Japan

Osaka Women's Junior College 3‐8‐1 Kasugaoka Fujiidera Osaka 583‐8558 Japan

Seed Compounds Exploratory Unit for Drug Discovery Platform RIKEN Center for Sustainable Resource Science 2‐1 Hirosawa Wako Saitama 351‐0198 Japan

Chemical Genomics Research Group RIKEN Center for Sustainable Resource Science 2‐1 Hirosawa Wako Saitama 351‐0198 Japan

School of Life Sciences Tokyo University of Pharmacy and Life Sciences 1432‐1 Horinouchi Hachioji Tokyo 192‐0392 Japan

Biofunctional Chemistry Laboratory A. Butlerov Institute of Chemistry Kazan Federal University 18 Kremlyovskaya Street Kazan 420008 Russian Federation

Department of Pathology (C3) Graduate School of Medicine Osaka University 2‐2 Yamadaoka Suita Osaka 565‐0871 Japan

GlycoTargeting Research Laboratory RIKEN Baton Zone Program 2‐1 Hirosawa Wako Saitama 351‐0198 Japan

References

Reference metadata was not supplied for this record.