journal article·2018-05Open access

Microfluidic Devices: Integrated Microfluidic Device for Drug Studies of Early C. Elegans Embryogenesis (Adv. Sci. 5/2018)

Li Dong, Radek Jankele, Matteo Cornaglia, Thomas Lehnert, Pierre Gönczy, Martin A. M. Gijs

Advanced Science· Volume 5· Issue 5

Abstract

The feasibility of time-controlled and reversible drug delivery to Caenorhabditis elegans (C. elegans) embryos immobilized on-chip is demonstrated by regulated blocking of cytokinesis using Cytochalasin-D. In article 1700751 by Martin A. M. Gijs and co-workers, the implementation of versatile microfluidic protocols, including time-controlled and reversible drug delivery to on-chip, immobilized embryos, demonstrates the potential of the reported device for biochemical and pharmacological assays.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: 3D Printing in Biomedical Research

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Affiliations

Laboratory of Microsystems Ecole Polytechnique Fédérale de Lausanne (EPFL) Lausanne 1015 Switzerland

Swiss Institute for Experimental Cancer Research (ISREC) School of Life Sciences Ecole Polytechnique Fédérale de Lausanne (EPFL) Lausanne 1015 Switzerland

References

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