journal article·2018-02Open access

Microfluidics: Guidance and Self‐Sorting of Active Swimmers: 3D Periodic Arrays Increase Persistence Length of Human Sperm Selecting for the Fittest (Adv. Sci. 2/2018)

Thiruppathiraja Chinnasamy, James L. Kingsley, Fatih Inci, Paul J. Turek, Mitchell P. Rosen, Barry Behr, Erkan Tüzel, Utkan Demirci

Advanced Science· Volume 5· Issue 2

Abstract

A model-driven design featuring pillar arrays that efficiently and non-invasively isolate highly motile and morphological normal sperm, with normal epigenetic global methylation, is presented by Erkan Tüzel, Utkan Demirci, and co-workers in article number 1700531. The image shows the Simple Periodic ARray for Trapping And isolatioN (SPARTAN) device sorting the unshapely and damaged sperm (in pink) from healthier sperm (blue). The unshapely sperm are diverted by the pillars in the device going in circles and do not emerge from the labrynth of the pillars in the system. In the image, pink and blue colors are used for illustration purposes only and do not denote the presence of an X or Y chromosome.
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Research context

OpenAlex topics: Modular Robots and Swarm Intelligence · Molecular Communication and Nanonetworks · Micro and Nano Robotics

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Affiliations

Bio‐Acoustic MEMS in Medicine (BAMM) Laboratory Canary Center at Stanford for Cancer Early Detection Department of Radiology Stanford School of Medicine Stanford University Palo Alto CA 94304 USA

Department of Physics Worcester Polytechnic Institute Worcester MA 01609 USA

The Turek Clinic San Francisco CA 94133 USA

Department of OBGYN University of California San Francisco School of Medicine San Francisco CA 94158 USA

Department of Obstetrics and Gynecology School of Medicine Stanford University Stanford CA 94305 USA

Department of Electrical Engineering (by courtesy) Stanford University Stanford CA 94305 USA

References

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