journal article·2022-03Open access

Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ

Hanna S. Schymik, Charlotte Dahlem, Ahmad Barghash, Alexandra K. Kiemer

Advanced Science· Volume 9· Issue 8

Abstract

Abstract Recently, first insights into the regulation and the role of the RNA‐binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti‐inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages.
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Research context

OpenAlex topics: RNA modifications and cancer · RNA Research and Splicing · Cancer-related molecular mechanisms research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Pharmacy Pharmaceutical Biology Saarland University Saarbruecken 66123 Germany

School of Electrical Engineering and Information Technology German Jordanian University Amman 11180 Jordan

Funding

Deutsche Forschungsgemeinschaft

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