journal article·2020-05Open access

Microvascular Scaffolds: A Biomimetic 3D‐Self‐Forming Approach for Microvascular Scaffolds (Adv. Sci. 9/2020)

Liucheng Zhang, Yi Xiang, Hongbo Zhang, Liying Cheng, Xiyuan Mao, Ning An, Lu Zhang, Jinxiong Zhou, Lianfu Deng, Yuguang Zhang, Xiaoming Sun, Hélder A. Santos, Wenguo Cui

Advanced Science· Volume 7· Issue 9

Abstract

Inspired by drying-driven curling of apple peels, hydrogel-based micro-scaled hollow tubules are proposed in article number 1903553 by Yuguang Zhang, Xiaoming Sun, Hélder A. Santos, Wenguo Cui, and co-workers for biomimicking microvessels with diameters of 50–500 μm, which promote microcirculation and improve the survival of random skin flaps. The 3D-shape-morphing technique is of great flexibility and potential to lay the foundation for the construction of complex vascular networks, such as Y-branches, anastomosis rings, and triangle loops.
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Research context

OpenAlex topics: Tissue Engineering and Regenerative Medicine · 3D Printing in Biomedical Research

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Affiliations

Department of Plastic and Reconstructive Surgery Shanghai Ninth People's Hospital Shanghai JiaoTong University School of Medicine 639 Zhi Zao Ju Road Shanghai 200011 P. R. China

Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China

Department of Pharmaceutical Sciences Laboratory and Turku Center for Biotechnology Åbo Akademi University Turku FI‐20520 Finland

State Key Laboratory for Strength and Vibration of Mechanical Structures School of Aerospace Xi'an Jiaotong University Xi'an 710049 P. R. China

Drug Research Program Division of Pharmaceutical Chemistry and Technology Faculty of Pharmacy University of Helsinki Helsinki FI‐00014 Finland

Helsinki Institute of Life Science (HiLIFE) University of Helsinki Helsinki FI‐00014 Finland

References

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