journal article·2022-06Open access

Distinct Stress‐Dependent Signatures of Cellular and Extracellular tRNA‐Derived Small RNAs (Adv. Sci. 17/2022)

Guoping Li, Aidan C. Manning, Alex Bagi, Xinyu Yang, Priyanka Gokulnath, Michail Spanos, Jonathan Howard, Patricia P. Chan, Thadryan Sweeney, Robert Kitchen, Haobo Li, Brice D. Laurent, Sary F. Aranki, Maria I. Kontaridis, Louise C. Laurent, Kendall Van Keuren‐Jensen, Jochen Muehlschlegel, Todd M. Lowe, Saumya Das

Advanced Science· Volume 9· Issue 17

Abstract

Extracellular tRNA‐Derived Small RNAs In article number 2200829, Saumya Das and co‐workers provide a comprehensive landscape for the signature of cellular and extracellular tRNA‐derived small RNAs (tDRs) in response to different stressors. They also determine a distinct fragmentation pattern for extracellular tDRs distinct from cellular tDRs and investigate the basis of their biogenesis and stability. [Image: see text]
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Research context

OpenAlex topics: RNA modifications and cancer · RNA and protein synthesis mechanisms · RNA Research and Splicing

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