journal article·2018-03Open access

Cancer Treatment: Enhanced Photodynamic Cancer Treatment by Mitochondria‐Targeting and Brominated Near‐Infrared Fluorophores (Adv. Sci. 3/2018)

Ilkoo Noh, DaeYong Lee, Heegon Kim, Chan‐Uk Jeong, Yunsoo Lee, Jung‐Oh Ahn, Hoon Hyun, Ji‐Ho Park, Yeu‐Chun Kim

Advanced Science· Volume 5· Issue 3

Abstract

The photodynamic therapy effect and mechanism of mitochondria targeting photodynamic therapeutic agents (MitDt) are reported. The MitDt is taken in by the cancer mitochondria and subsequently releases singlet oxygen () when irradiated with a 662 nm laser, thereby inducing apoptosis of cancer. The underlying mechanism is discussed in article number 1700481 by Yeu-Chun Kim and co-workers.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies

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Affiliations

Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 305‐701 South Korea

Department of Bio and Brain Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 305‐701 South Korea

Korea Research Institute of Bioscience and Biotechnology 52 Eoeun‐dong Daejon 305‐333 South Korea

Department of Biomedical Sciences Chonnam National University Medical School Gwangju 501‐746 South Korea

References

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