DataVXAdvanced SciencePaper
journal article·2018-05Open access

Tissue Engineering: A Modular Strategy to Engineer Complex Tissues and Organs (Adv. Sci. 5/2018)

Anna D. Dikina, Daniel S. Alt, Samuel Herberg, Alexandra McMillan, Hannah A. Strobel, Zijie Zheng, Meng Cao, Bradley P. Lai, Oju Jeon, Victoria Ivy Petsinger, Calvin U. Cotton, Marsha W. Rolle, Eben Alsberg

Advanced Science· Volume 5· Issue 5
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Source abstract

Abstract

In article number 1700402, Eben Alsberg and co-workers report the engineering of tri-tissue tracheas using a scaffold-free approach that allows for the integration of structural cartilage rings, prevascular blood vessel networks, and epithelial cells into a single construct. Neotracheas of various dimensions, including human size, are formed via cellular self-assembly. Prevascular tracheas are subcutaneously implanted into mice and demonstrate anastamosis with and perfusion by host vasculature.
Source: openalex_inverted_index · Quality: baseline

Research context

Biomaterials

OpenAlex topics: Tissue Engineering and Regenerative Medicine

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Affiliations

Department of Biomedical Engineering Case Western Reserve University 10900 Euclid Ave Cleveland OH 44106 USA

Department of Pathology Case Western Reserve University 10900 Euclid Ave Cleveland OH 44106 USA

Department of Biomedical Engineering Worcester Polytechnic Institute 100 Institute Road Worcester MA 01609 USA

Department of Pediatrics Department of Physiology and Biophysics Case Western Reserve University 10900 Euclid Ave Cleveland OH 44106 USA

Department of Orthopaedic Surgery National Center for Regenerative Medicine Case Western Reserve University 10900 Euclid Ave Cleveland OH 44106 USA

References

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