journal article·2022-08Open access

A 3D Bioprinted in vitro Model of Neuroblastoma Recapitulates Dynamic Tumor‐Endothelial Cell Interactions Contributing to Solid Tumor Aggressive Behavior (Adv. Sci. 23/2022)

Liqun Ning, Jenny Shim, Martin L. Tomov, Rui Liu, Riya Mehta, Andrew Mingee, Boeun Hwang, Linqi Jin, Athanasios Mantalaris, Chunhui Xu, Morteza Mahmoudi, Kelly C. Goldsmith, Vahid Serpooshan

Advanced Science· Volume 9· Issue 23

Abstract

3D Bioprinted in vitro Model of Neuroblastoma Neuroblastoma (NB) accounts for 50% of all cancers in infants with substantial mortality. Due to the lack of robust experimental models, the role of NB microenvironment in tumor progression is poorly understood. Through integrating 3D bioprinting and NB spheroid technologies, in article number 2200244, Kelly C. Goldsmith, Vahid Serpooshan, and co‐workers create an in vitro vascular model of NB and examine the tumor function within an endothelialized microenvironment. [Image: see text]
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Research context

OpenAlex topics: Neuroblastoma Research and Treatments · 3D Printing in Biomedical Research · Mesenchymal stem cell research

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