journal article·2023-09Open access

Self‐Propelled Proteomotors with Active Cell‐Free mtDNA Clearance for Enhanced Therapy of Sepsis‐Associated Acute Lung Injury (Adv. Sci. 27/2023)

Weichang Huang, Lihong Wen, Hao Tian, Jiamiao Jiang, Meihuan Liu, Yicheng Ye, Junbin Gao, Ruotian Zhang, Fei Wang, Huaan Li, Lihan Shen, Fei Peng, Yingfeng Tu

Advanced Science· Volume 10· Issue 27

Abstract

Self-Propelled Proteomotors with active cf-mtDNA Clearance In article number 2301635, Lihan Shen, Fei Peng, Yingfeng Tu, and co-workers develop a novel DNase-I-powered nanomotor system which efficiently eliminates cf-mtDNA and inhibits TLR9-mediated inflammatory activation of alveolar macrophages as a novel strategy for sepsis-associated acute lung injury treatment.
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Research context

OpenAlex topics: Micro and Nano Robotics · Advanced Nanomaterials in Catalysis

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