DataVXAdvanced SciencePaper
journal article·2019-03Open access

Self‐Assembly: Targeted Therapy against Metastatic Melanoma Based on Self‐Assembled Metal‐Phenolic Nanocomplexes Comprised of Green Tea Catechin (Adv. Sci. 5/2019)

Ke Li, Gao Xiao, Joseph J. Richardson, Blaise L. Tardy, Hirotaka Ejima, Wen Huang, Junling Guo, Xuepin Liao, Bi Shi

Advanced Science· Volume 6· Issue 5
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Source abstract

Abstract

The targeted therapy of metastatic melanoma is a highly challenging therapeutic goal that has received only limited attention to date. In article number 1801688, Junling Guo, Xuepin Liao, and co-workers report the self-assembly of therapeutic nanocomplexes composed of green tea polyphenols, epigallocatechin-3-gallate (EGCG), and lanthanide metal ions (Sm3+). These nanocomplexes show remarkable targeted therapy against melanoma and prevent aggressive migration to main organs with no adverse side effects.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Advanced Nanomaterials in Catalysis · Tea Polyphenols and Effects · Advanced Computing and Algorithms

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Affiliations

Department of Biomass Chemistry and Engineering Sichuan University Chengdu 610065 China

Laboratory of Ethnopharmacology Regenerative Medicine Research Center West China Hospital Sichuan University Chengdu Sichuan 610041 China

Wyss Institute for Biologically Inspired Engineering John A. Paulson School of Engineering and Applied Sciences Harvard University Boston MA 02115 USA

Department of Environmental Science and Engineering College of Environment and Resources Fuzhou University Fuzhou 350108 China

ARC Centre of Excellence in Convergent Bio‐Nano Science and Technology and Department of Chemical and Biomolecular Engineering The University of Melbourne Parkville Victoria 3010 Australia

Department of Bioproducts and Biosystems School of Chemical Engineering Aalto University P. O. Box 16300 00076 Finland

Department of Materials Engineering The University of Tokyo 7‐3‐1 Hongo Bunkyo‐ku Tokyo 113‐8656 Japan

National Engineering Laboratory for Clean Technology of Leather Manufacture Sichuan University Chengdu Sichuan 610065 China

References

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