journal article·2022-01Open access

Polydopamine Nanoparticle‐Mediated Dopaminergic Immunoregulation in Colitis (Adv. Sci. 1/2022)

Juanjuan Li, Weiliang Hou, Sisi Lin, Lu Wang, Chao Pan, Feng Wu, Jinyao Liu

Advanced Science· Volume 9· Issue 1

Abstract

Dopaminergic Immunoregulation In article number 2104006 by Jinyao Liu and co‐workers, the dopaminergic system is exploited to suppress hyperactive immune responses in local inflamed tissues by polydopamine nanoparticles, which stimulate regulatory T lymphocytes and dendritic cells, while inhibit T helper cells to assist the reversion of inflammatory responses. The application of dopaminergic immunoregulation is further disclosed by combining with oral probiotics that can modulate the gut microbiota for treating colitis. [Image: see text]
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Research context

OpenAlex topics: Gut microbiota and health · Vagus Nerve Stimulation Research · COVID-19 Impact on Reproduction

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