DataVXAdvanced SciencePaper
journal article·2019-06Open access

Bone Regeneration: A Magnesium‐Enriched 3D Culture System that Mimics the Bone Development Microenvironment for Vascularized Bone Regeneration (Adv. Sci. 12/2019)

Sihan Lin, Guangzheng Yang, Fei Jiang, Mingliang Zhou, Shi Yin, Yanmei Tang, Tingting Tang, Zhiyuan Zhang, Wenjie Zhang, Xinquan Jiang

Advanced Science· Volume 6· Issue 12
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Source abstract

Abstract

Inspired by the correlation between MagT1 and embryonic bone development, a magnesium-enriched 3D culture system is fabricated to provide embryonic-like microenvironment for stem cells in article number 1900209 by Wenjie Zhang, Xinquan Jiang, and co-workers. Mg2+ via MagT1 stimulates both osteogenic differentiation and neovascularization. An obvious vascularized bone regeneration is achieved in vivo using such magnesium-enriched cell vehicles.
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Research context

OpenAlex topics: Bone Tissue Engineering Materials

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Affiliations

Department of Prosthodontics Shanghai Engineering Research Center of Advanced Dental Technology and Materials Shanghai Research Institute of Stomatology National Clinical Research Center for Oral Diseases Shanghai Key Laboratory of Stomatology Ninth People's Hospital College of Stomatology Shanghai JiaoTong University School of Medicine 639 Zhizaoju Road Shanghai 200011 P. R. China

Department of Orthopaedic Surgery Ninth People's Hospital Shanghai JiaoTong University School of Medicine 639 Zhizaoju Road Shanghai 200011 P. R. China

Department of Oral and Maxillofacial‐Head and Neck Oncology Shanghai Research Institute of Stomatology National Clinical Research Center for Oral Diseases Shanghai Key Laboratory of Stomatology Ninth People's Hospital College of Stomatology Shanghai JiaoTong University School of Medicine 639 Zhizaoju Road Shanghai 200011 P. R. China

References

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