journal article·2022-05Open access

Bile Acid–Microbiome Interaction Promotes Gastric Carcinogenesis (Adv. Sci. 16/2022)

Shouli Wang, Junliang Kuang, Hongwei Zhang, Wenlian Chen, Xiaojiao Zheng, Jieyi Wang, Fengjie Huang, Kun Ge, Mengci Li, Mingliang Zhao, Cynthia Rajani, Jinshui Zhu, Aihua Zhao, Wei Jia

Advanced Science· Volume 9· Issue 16

Abstract

New Strategy for the Prevention of Gastric Cancer Bile reflux can promote gastric carcinogenesis through activation of the IL‐6/JAK1‐STAT3 signaling pathway. Inhibition of STAT3 by cryptotanshinone can alleviate this carcinogenic effect, thus providing a new strategy for the prevention of gastric cancer associated with bile reflux. More details can be found in article number 2200263 by Aihua Zhao, Wei Jia, and co‐workers. [Image: see text]
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Research context

OpenAlex topics: Mycobacterium research and diagnosis · Medical Research and Treatments · Gut microbiota and health

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