journal article·2018-03Open access

Nanocomposite Hydrogels: 3D‐Bioprinted Osteoblast‐Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo (Adv. Sci. 3/2018)

Xinyun Zhai, Changshun Ruan, Yufei Ma, Delin Cheng, Mingming Wu, Wenguang Liu, Xiaoli Zhao, Haobo Pan, William Weijia Lu

Advanced Science· Volume 5· Issue 3

Abstract

In article number 1700550, Changshun Ruan, Haobo Pan, William Weijia Lu, and co-workers report the development of an osteoblast-laden nanocomposite hydrogel construct for bone regeneration. The construct is created using a two-channel, 3D-bioprinting method and exhibits high cell viability in the short term after bioprinting. In the long term, it is shown to have excellent osteogenic capabilities, both in vitro and in vivo, because of the bioactive ions that are gradually released.
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Research context

OpenAlex topics: Periodontal Regeneration and Treatments · Mesenchymal stem cell research

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Affiliations

Research Center for Human Tissue and Organs Degeneration Institute Biomedical and Biotechnology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China

Department of Orthopaedic and Traumatology The University of Hong Kong 21 Sassoon Road Pokfulam Hong Kong 999077 China

School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional Materials Tianjin University Tianjin 300352 China

References

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