journal article·2026-04Open access

WUSCHEL Transcription Factor: From Stem Cell Maintenance to Crop Improvement

Zishan Ahmad, Muthusamy Ramakrishnan, Rajeev K. Varshney, Anwar Shahzad, Shamsur Rehman, Bijaya Pant, Qiang Wei

Advanced Science· Volume 13· Issue 24

Abstract

ABSTRACT The WUSCHEL (WUS) transcription factor, long recognized as a master regulator of stem cell maintenance in the shoot apical meristem (SAM), has expanded in significance as a multifaceted tool in plant biotechnology. With an emphasis on its new uses in crop regeneration, somatic embryogenesis (SE), stress tolerance, and developmental regulation in cereals, legumes, and other plant species, this review summarizes recent developments on WUS function outside of Arabidopsis . We emphasize how insights from WUS biology can be translated into practical strategies to improve yield, adaptability, and resilience, while also enhancing in vitro tissue culture systems. The objective of this review is to establish WUS as a crucial molecular target for future crop genetic improvement and sustainable farming methods by highlighting the current knowledge gaps and suggesting future directions.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Plant Molecular Biology Research · Plant tissue culture and regeneration · Polysaccharides and Plant Cell Walls

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Tree Genetics and Breeding Co‐Innovation Center for Sustainable Forestry in Southern China Bamboo Research Institute Nanjing Forestry University Nanjing Jiangsu China

WA State Agricultural Biotechnology Centre Centre for Crop and Food Innovation Food Futures Institute Murdoch University Murdoch WA Australia

Plant Biotechnology Section Department of Botany Aligarh Muslim University Aligarh India

State Key Laboratory of Wheat Improvement Peking University Institute of Advanced Agricultural Sciences Shandong Laboratory of Advanced Agriculture Sciences in Weifang Weifang Shandong China

Central Department of Botany Tribhuvan University Kirtipur Nepal

Funding

National Natural Science Foundation of China · Natural Science Foundation of Jiangsu Province

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