Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling (Adv. Sci. 31/2025)
Source abstract
Abstract
Nuclear Tension In article number 2502375, Dong-Hwee Kim, and co-workers present a mechanobiological mechanism of progerin-induced wrinkling of nuclear surface. They demonstrate a new biophysical aging process that the abnormal nuclear shape leads to the regulation of aging-dependent changes of gene profiles.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nuclear Structure and Function · Microtubule and mitosis dynamics · Cellular transport and secretion
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