Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications (Adv. Sci. 21/2025)

Histone Deacetylase 6 in Ciliopathies HDAC6's dual role in ciliopathies is portrayed through Nezha, symbolizing its complex regulatory function in ciliary dynamics. Merging mythology with science, the image highlights HDAC6's influence on cilia-related signaling and disease progression, and the therapeutic promise of selective inhibitors in restoring ciliary integrity and maintaining cellular homeostasis. More details can be found in article number 2412921 by Kaidi Ren, Jie Ran, Yang Yang, and co-workers.