A Bio‐Responsive Hydrogel with Spatially Heterogeneous Structure for Treating Infectious Tissue Injuries (Adv. Sci. 23/2025)

Bio-Responsive Hydrogel This frontispiece highlights a bio-responsive hydrogel featuring Preyssler-type polyoxometalates (POMs) for sodium ion-triggered silver release. The hydrogel delivers potent and broad-spectrum antibacterial activity while maintaining biocompatibility. Its spatially heterogeneous structure enables controlled release and tissue integration, offering a promising therapeutic strategy for repairing infectious soft and hard tissue injuries under complex pathological conditions. More details can be found in article number 2500088 by Yan Wang, Wei Teng, Qianqian Yu, Weichang Li, and co-workers.