journal article·2025-02Open access

Pathophysiology‐Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain (Adv. Sci. 8/2025)

Wenkai Wang, Yan Wang, Xinle Huang, Peng Wu, Lanlan Li, Yang Zhang, Yihui Chen, Zhiyu Chen, Changqing Li, Yue Zhou, Jianxiang Zhang

Advanced Science· Volume 12· Issue 8

Abstract

Combination Nanoanalgesic for Neuropathic Pain In article number 2405483, Yue Zhou, Jianxiang Zhang, and co-workers report a combination nanoanalgesic composed of inflammation-resolving nanomicelles and an analgesic peptide targeting the calcium channel α2δ1 subunit. This innovative nanotherapy effectively inhibits neuroinflammation, promotes nerve regeneration, and provides analgesic activity, thereby affording synergistic effects for the treatment of neuropathic pain induced by nerve injury.
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Research context

OpenAlex topics: Anesthesia and Neurotoxicity Research · 3D Printing in Biomedical Research · Nanoparticle-Based Drug Delivery

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