journal article·2024-11Open access

Preserving the Immune‐Privileged Niche of the Nucleus Pulposus: Safeguarding Intervertebral Discs from Degeneration after Discectomy with Synthetic Mucin Hydrogel Injection (Adv. Sci. 43/2024)

Huan Wang, Song Chen, Zhao Liu, Qingchen Meng, Rita Sobreiro‐Almeida, Ling Liu, Håvard Jostein Haugen, Jiaying Li, João F. Mano, Youzhi Hong, Thomas Crouzier, Hongji Yan, Bin Li

Advanced Science· Volume 11· Issue 43

Abstract

Mucin Hydrogels The study by Song Chen, Hongji Yan, Bin Li, and co-workers unequivocally establishes the multifaceted utility of mucin hydrogels (Muc-gels), showcasing their efficacy as both a physical shielding barrier and an immune-isolating barrier for nucleus pulposus. This novel dual-functionality presents a promising avenue for mitigating the recurrence rate of discectomy and impeding the progression of intervertebral disc degeneration. More details can be found in article number 2404496.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Spine and Intervertebral Disc Pathology · Medical Imaging and Analysis · Musculoskeletal pain and rehabilitation

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