journal article·2019-11Open access

Tissue Expansion: Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio (Adv. Sci. 22/2019)

Han‐Eol Park, Dongkil Choi, Ji Su Park, Changgon Sim, Sohyun Park, Sunah Kang, Hyunsoo Yim, Myungsun Lee, Jaeyoun Kim, Jinyoung Pac, Kunsoo Rhee, Junho Lee, Yunjong Lee, Yan Lee, Sung‐Yon Kim

Advanced Science· Volume 6· Issue 22

Abstract

In article number 1901673, Yan Lee, Sung-Yon Kim, and co-workers develop ZOOM, a new tissue expansion technique based on the hydrogel conversion reaction, to enable scalable and isotropic expansion of biological samples with easily tunable expansion ratio (up to eightfold). This method allows for simple and flexible expansion of a wide range of biological samples, from bacteria to human brain tissues, for super-resolution imaging of samples with ordinary microscopes.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research

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Affiliations

Institute of Molecular Biology and Genetics Seoul National University Seoul 08826 South Korea

Department of Biological Sciences Seoul National University Seoul 08826 South Korea

Department of Chemistry Seoul National University Seoul 08826 South Korea

Division of Pharmacology Department of Molecular Cell Biology Samsung Biomedical Research Institute Sungkyunkwan University School of Medicine Suwon 16419 South Korea

References

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