journal article·2024-02Open access

Ligand‐Screened Cerium‐Based MOF Microcapsules Promote Nerve Regeneration via Mitochondrial Energy Supply (Adv. Sci. 6/2024)

Xinzhao Jiang, Wei Wang, Jincheng Tang, Meng Han, Yichang Xu, Lichen Zhang, Jie Wu, Yiyang Huang, Zhouye Ding, Huiwen Sun, Kun Xi, Yong Gu, Liang Chen

Advanced Science· Volume 11· Issue 6

Abstract

Spinal Cord Injury The cover is inspired by the murals of the Dunhuang Mogao frescoes, and the elements from this grotto art are used to reconstruct a cross-section of the spinal cord, because the spinal cord is as intricate and beautifully crafted works of art as frescoes. In article number 2306780, Kun Xi, Yong Gu, Liang Chen, and co-workers construct a novel cellular “energy microcapsule” (appearing as the flying apsaras from grotto culture) for injured spinal cords, visualized by the cracks that appear in the frescoes. This energy microcapsule rebalances the immune environment and promotes neural repair by correcting the mitochondrial energy deficiency in macrophages and neurons, ultimately to mend the “frescoes”.
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Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Metal-Organic Frameworks: Synthesis and Applications · Organoselenium and organotellurium chemistry

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