Tumor‐Targeted FABP5/STING Cascade Promote Radiofrequency Ablation Induced Ferroptosis and Intratumoral Immune Rewiring in Hepatocellular Carcinoma (Adv. Sci. 45/2025)

Bufu Tang; Xiaojie Zhang; Yiting Sun; Jinhua Luo; Qiaoyou Weng; Cong Zhang; Zilin Wang; Shiji Fang; Yangrui Xiao; Liyun Zheng; Jianfei Tu; Rongfang Qiu; Yang Yang; Zhongwei Zhao; Weiqian Chen; Minjiang Chen; Jiansong Ji

doi:10.1002/advs.72596

journal article·2025-12Open access

Tumor‐Targeted FABP5/STING Cascade Promote Radiofrequency Ablation Induced Ferroptosis and Intratumoral Immune Rewiring in Hepatocellular Carcinoma (Adv. Sci. 45/2025)

Bufu Tang, Xiaojie Zhang, Yiting Sun, Jinhua Luo, Qiaoyou Weng, Cong Zhang, Zilin Wang, Shiji Fang, Yangrui Xiao, Liyun Zheng, Jianfei Tu, Rongfang Qiu, Yang Yang, Zhongwei Zhao, Weiqian Chen, Minjiang Chen, Jiansong Ji

Advanced Science· Volume 12· Issue 45

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Source abstract

Abstract

Hepatocellular Carcinoma Inspired by Nezha Conquers the Dragon King, this cover depicts a nanosystem combatting hepatocellular carcinoma: a Fire-Tipped Spear (RFA), Sky-Conquering Ribbon (sgFABP5 editing), and Universe Ring (SPIO nanoparticles) overcome the immunosuppressive microenvironment. More details can be found in the Research Article by Jiansong Ji, Weiqian Chen, Minjiang Chen, and co-workers (DOI: 10.1002/advs.202507864).

Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Ferroptosis and cancer prognosis · interferon and immune responses · Chromatin Remodeling and Cancer

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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