journal article·2024-12Open access

Thermally Drawn Polymeric Catheters for MR‐Guided Cardiovascular Intervention

Mohamed E. M. K. Abdelaziz, Libaihe Tian, Thomas Lottner, Simon Reiss, Timo Heidt, Alexander Maier, Klaus Düring, Constantin von zur Mühlen, Michael Bock, Eric Yeatman, Guang‐Zhong Yang, Burak Temelkuran

Advanced Science· Volume 11· Issue 45

Abstract

Abstract Cardiovascular diseases (CVDs), including congenital heart diseases (CHD), present significant global health challenges, emphasizing the need for safe and effective treatment modalities. Fluoroscopy‐guided endovascular interventions are widely utilized but raise concerns about ionizing radiation, especially in pediatric cases. Magnetic resonance imaging (MRI) offers a radiation‐free alternative with superior soft tissue visualization and functional insights. However, the lack of compatible instruments remains a major obstacle. An adapted thermal drawing platform that enables low‐cost and rapid prototyping of instruments for MR‐guided endovascular interventions is introduced. This platform is demonstrated through the development of two exemplary catheter systems: a tendon‐driven steerable catheter with helical lumina and an active tracking Tiger‐shaped catheter with an embedded coaxial wire. These catheters exhibit mechanical properties comparable to commercial counterparts and show promising outcomes in both in vitro and in vivo feasibility testing. This scalable thermal drawing platform addresses the limitations of existing manufacturing approaches and facilitates the exploration of diverse designs, potentially accelerating advancements in catheter technologies for MR‐guided cardiovascular interventions.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Congenital Heart Disease Studies · Cardiac Valve Diseases and Treatments · Aortic Disease and Treatment Approaches

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

The Hamlyn Centre for Robotic Surgery Imperial College London London SW7 2AZ UK

Department of Electrical and Electronic Engineering Faculty of Engineering Imperial College London London SW7 2AZ UK

Department of Metabolism Digestion, and Reproduction Faculty of Medicine Imperial College London London SW7 2AZ UK

Department of Diagnostic and Interventional Radiology Medical Physics Faculty of Medicine, University of Freiburg 79106 Freiburg Germany

Department of Cardiology and Angiology University Heart Center Freiburg – Bad Krozingen Faculty of Medicine University of Freiburg 79106 Freiburg Germany

MaRVis Interventional GmbH 82467 Garmisch‐Partenkirchen Germany

Institute of Medical Robots Shanghai Jiao Tong University Shanghai 200240 China

The Rosalind Franklin Institute Didcot OX11 0QS UK

Funding

Deutsche Forschungsgemeinschaft · Engineering and Physical Sciences Research Council

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