Implementation of Arithmetic Functions on a Simple and Universal Molecular Beacon Platform
Source abstract
Abstract
Diverse advanced logic circuits are fabricated to implement arithmetic functions based on a simple and single molecular beacon platform, including half adder, half subtractor, full adder, full subtractor, and a digital comparator. Dual fluorescence outputs are generated in parallel and a constant threshold value is set to build all the logic circuits. The developed enzyme-free DNA system provides a novel prototype for the design of high-level molecular logic circuits on a biomolecular platform.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques · DNA and Biological Computing · DNA and Nucleic Acid Chemistry
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Changchun 130022 China
Graduate School of the Chinese Academy of Sciences Beijing 100039 China
Department of Nanomedicine Houston Methodist Research Institute Houston TX 77030 USA
Department of Cell and Developmental Biology Weill Medical College of Cornell University NY 10065 USA
Funding
National Natural Science Foundation of China
References (62)
Show source-provided references
1. 10.1038/3501825910.1038/35018259 ↗
2. 10.1126/science.106952810.1126/science.1069528 ↗
3. 10.1021/nn406523y10.1021/nn406523y ↗
4. 10.1002/978047071088310.1002/9780470710883 ↗
5. de Silva A. P. · 2013
6. 10.1002/978352764544210.1002/9783527645442 ↗
7. 10.1038/454417a10.1038/454417a ↗
8. 10.1038/nnano.2007.18810.1038/nnano.2007.188 ↗
9. 10.1002/cphc.20120015710.1002/cphc.201200157 ↗
10. 10.1002/anie.20090670510.1002/anie.200906705 ↗
11. 10.1021/cr068403q10.1021/cr068403q ↗
12. 10.1166/jctn.2011.170710.1166/jctn.2011.1707 ↗
13. 10.1002/anie.20070087910.1002/anie.200700879 ↗
14. 10.1039/b806038j10.1039/b806038j ↗
15. 10.1038/nbt86210.1038/nbt862 ↗
16. 10.1038/3510653310.1038/35106533 ↗
17. 10.1038/nbt1209-109110.1038/nbt1209-1091 ↗
18. 10.1016/j.biomaterials.2011.06.04010.1016/j.biomaterials.2011.06.040 ↗
19. 10.1002/smll.20110275810.1002/smll.201102758 ↗
20. 10.1002/anie.20100440610.1002/anie.201004406 ↗
21. 10.1126/science.120052010.1126/science.1200520 ↗
22. 10.1038/nrg319710.1038/nrg3197 ↗
23. 10.1021/ar500053810.1021/ar5000538 ↗
24. 10.1039/C1CC15329C10.1039/C1CC15329C ↗
25. 10.1039/B820280J10.1039/B820280J ↗
26. 10.1002/anie.20060399010.1002/anie.200603990 ↗
27. 10.1002/anie.20090683410.1002/anie.200906834 ↗
28. 10.1021/ja802845z10.1021/ja802845z ↗
29. 10.1021/ja058564w10.1021/ja058564w ↗
30. 10.1021/ja203456h10.1021/ja203456h ↗
31. 10.1021/jp207812a10.1021/jp207812a ↗
32. 10.1039/c2jm14973g10.1039/c2jm14973g ↗
33. 10.1021/jp055741710.1021/jp0557417 ↗
34. 10.1021/jp804658b10.1021/jp804658b ↗
35. 10.1021/ja065457910.1021/ja0654579 ↗
36. 10.1038/nature1114910.1038/nature11149 ↗
37. 10.1002/anie.20120235610.1002/anie.201202356 ↗
38. 10.1002/smll.20070011310.1002/smll.200700113 ↗
39. 10.1021/ja029663210.1021/ja0296632 ↗
40. 10.1021/bi051871u10.1021/bi051871u ↗
41. 10.1038/am.2012.110.1038/am.2012.1 ↗
42. 10.1039/C1CC14518E10.1039/C1CC14518E ↗
43. 10.1038/nnano.2014.5810.1038/nnano.2014.58 ↗
44. 10.1039/c3sc50924a10.1039/c3sc50924a ↗
45. 10.1002/anie.20050331410.1002/anie.200503314 ↗
46. 10.1038/nnano.2010.8810.1038/nnano.2010.88 ↗
47. 10.1039/C4SC00914B10.1039/C4SC00914B ↗
48. 10.1038/nature0255110.1038/nature02551 ↗
49. 10.1021/ja905125b10.1021/ja905125b ↗
50. 10.1002/978352764548010.1002/9783527645480 ↗
51. 10.1088/0957-4484/17/2/R0110.1088/0957-4484/17/2/R01 ↗
52. 10.1038/nmat146910.1038/nmat1469 ↗
53. 10.1038/nbt0396-30310.1038/nbt0396-303 ↗
54. 10.1073/pnas.100917210710.1073/pnas.1009172107 ↗
55. 10.1039/C4SC02032D10.1039/C4SC02032D ↗
56. 10.1002/anie.20130127810.1002/anie.201301278 ↗
57. 10.1021/cr900323b10.1021/cr900323b ↗
58. 10.1021/jp061749k10.1021/jp061749k ↗
59. 10.1038/am.2013.6610.1038/am.2013.66 ↗
60. 10.1126/science.113249310.1126/science.1132493 ↗
61. 10.1038/nnano.2007.2310.1038/nnano.2007.23 ↗
62. 10.1039/b902484k10.1039/b902484k ↗