Photoacid Generators for Biomedical Applications
Source abstract
Abstract
Abstract Photoacid generators (PAGs) are compounds capable of producing hydrogen protons (H+) upon irradiation, including irreversible and reversible PAGs, which have been widely studied in photoinduced polymerization and degradation for a long time. In recent years, the applications of PAGs in the biomedical field have attracted more attention due to their promising clinical value. So, an increasing number of novel PAGs have been reported. In this review, the recent progresses of PAGs for biomedical applications is systematically summarized, including tumor treatment, antibacterial treatment, regulation of protein folding and unfolding, control of drug release and so on. Furthermore, a concept of water‐dependent reversible photoacid (W‐RPA) and its antitumor effect are highlighted. Eventually, the challenges of PAGs for clinical applications are discussed.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Luminescence and Fluorescent Materials · Photopolymerization techniques and applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Medical Technology Beijing Institute of Technology No. 5 South Street, Zhongguancun Haidian District Beijing 100081 China
Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry Chinese Academy of Sciences No. 29 Zhongguancun East Road, Haidian District Beijing 100190 China
University of Chinese Academy of Sciences No. 19A Yuquan Road Beijing 100049 China
Department of Laser Medicine The First Medical Centre Chinese PLA General Hospital No. 28 Fuxing Road, Haidian District Beijing 100853 China
Funding
National Key Research and Development Program of China · Beijing Institute of Technology Research Fund Program for Young Scholars
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