From Images to Genes: Radiogenomics Based on Artificial Intelligence to Achieve Non‐Invasive Precision Medicine in Cancer Patients
Source abstract
Abstract
Abstract With the increasing demand for precision medicine in cancer patients, radiogenomics emerges as a promising frontier. Radiogenomics is originally defined as a methodology for associating gene expression information from high‐throughput technologies with imaging phenotypes. However, with advancements in medical imaging, high‐throughput omics technologies, and artificial intelligence, both the concept and application of radiogenomics have significantly broadened. In this review, the history of radiogenomics is enumerated, related omics technologies, the five basic workflows and their applications across tumors, the role of AI in radiogenomics, the opportunities and challenges from tumor heterogeneity, and the applications of radiogenomics in tumor immune microenvironment. The application of radiogenomics in positron emission tomography and the role of radiogenomics in multi‐omics studies is also discussed. Finally, the challenges faced by clinical transformation, along with future trends in this field is discussed.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Radiomics and Machine Learning in Medical Imaging · Cancer Genomics and Diagnostics · Lung Cancer Diagnosis and Treatment
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Radiology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China
Hubei Key Laboratory of Molecular Imaging Wuhan 430022 China
Department of Ultrasound State Key Laboratory of Complex Severe and Rare Diseases Peking Union Medical College Hospital Chinese Academy of Medical. Sciences Peking Union Medical College Beijing 100730 China
Research Institute of Trustworthy Autonomous Systems and Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen 518055 China
School of Life Science and Technology Computational Biology Research Center Harbin Institute of Technology Harbin 150001 China
Funding
National Key Research and Development Program of China · National Natural Science Foundation of China · Fundamental Research Funds for the Central Universities
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