Pre‐Metastatic Niche: Biomaterial Scaffolds as Pre‐metastatic Niche Mimics Systemically Alter the Primary Tumor and Tumor Microenvironment (Adv. Healthcare Mater. 10/2018)

Brian A. Aguado; Rachel M. Hartfield; Grace G. Bushnell; Joseph T. Decker; Samira M. Azarin; Dhaval Nanavati; Matthew J. Schipma; Shreyas S. Rao; Robert S. Oakes; Yining Zhang; Jacqueline S. Jeruss; Lonnie D. Shea

doi:10.1002/adhm.201870040

journal article·2018-05Open access

Pre‐Metastatic Niche: Biomaterial Scaffolds as Pre‐metastatic Niche Mimics Systemically Alter the Primary Tumor and Tumor Microenvironment (Adv. Healthcare Mater. 10/2018)

Brian A. Aguado, Rachel M. Hartfield, Grace G. Bushnell, Joseph T. Decker, Samira M. Azarin, Dhaval Nanavati, Matthew J. Schipma, Shreyas S. Rao, Robert S. Oakes, Yining Zhang, Jacqueline S. Jeruss, Lonnie D. Shea

Advanced Healthcare Materials· Volume 7· Issue 10

Publisher page Open full text

Source abstract

Abstract

Biomaterial implants that mimic the premetastatic niche are shown to redirect immune and tumor cell populations in vivo. However, the systemic effects of premetastatic niche mimics on metastasis progression have yet to be characterized. In article 1700903 by Lonnie D. Shea and co-workers, synthetic biomaterial implants are shown to systemically alter the primary tumor and the tumor microenvironment to promote an invasion-suppressive phenotype. Cover art designed and produced by Stephen Alvey, University of Michigan, Department of Engineering.

Source: openalex_inverted_index · Quality: baseline

Research context

Biomaterials

OpenAlex topics: Tissue Engineering and Regenerative Medicine · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomedical Engineering Simpson Querrey Institute for BioNanotechnology Northwestern University Evanston IL 60208 USA

Department of Biomedical Engineering University of Michigan Ann Arbor MI 48105 USA

Department of Chemical Engineering and Materials Science University of Minnesota Minneapolis MN 55455 USA

Proteomics Core Facility Northwestern University Chicago IL 60611 USA

NUSeq Core Facility Northwestern University Chicago IL 60611 USA

Department of Chemical and Biological Engineering University of Alabama Tuscaloosa AL 35487 USA

Department of Surgery University of Michigan Ann Arbor MI 48105 USA

Department of Chemical Engineering University of Michigan Ann Arbor MI 48105 USA

References

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