journal article·2025-03

Advanced Carriers for Precise Delivery and Therapeutic Mechanisms of Traditional Chinese Medicines: Integrating Spatial Multi‐Omics and Delivery Visualization

Yusheng Zhang, Zhiguo Lu, Jing Guo, Qing Wang, Xin Zhang, Hongjun Yang, Xianyu Li

Advanced Healthcare Materials· Volume 14· Issue 6
Publisher page

Abstract

Abstract The complex composition of traditional Chinese medicines (TCMs) has posed challenges for in‐depth study and global application, despite their abundance of bioactive compounds that make them valuable resources for disease treatment. To overcome these obstacles, it is essential to modernize TCMs by focusing on precise disease treatment. This involves elucidating the structure‐activity relationships within their complex compositions, ensuring accurate in vivo delivery, and monitoring the delivery process. This review discusses the research progress of TCMs in precision disease treatment from three perspectives: spatial multi‐omics technology for precision therapeutic activity, carrier systems for precise in vivo delivery, and medical imaging technology for visualizing the delivery process. The aim is to establish a novel research paradigm that advances the precision therapy of TCMs.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Barrier Structure and Function Studies · Immune cells in cancer

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Beijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center China Academy of Chinese Medical Sciences Beijing 100700 P. R. China

State Key Laboratory of Biochemical Engineering, Institute of Process, Engineering Chinese Academy of Sciences Beijing 100190 P. R. China

Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering Chinese Academy of Sciences Beijing 100190 P. R. China

School of Life Sciences Beijing University of Chinese Medicine Beijing 100029 P. R. China

State Key Laboratory for Quality Ensurance and Sustainable Use of Dao‐di Herbs China Academy of Chinese Medical Sciences Beijing 100029 P. R. China

Funding

National Natural Science Foundation of China · Natural Science Foundation of Beijing Municipality

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