journal article·2025-03

Recent Development of Nanozymes for Combating Bacterial Drug Resistance: A Review

Lingping Xie, Haoyue Wu, Yuanfeng Li, Linqi Shi, Yong Liu

Advanced Healthcare Materials· Volume 14· Issue 8
Publisher page

Abstract

Abstract The World Health Organization has warned that without effective action, deaths from drug‐resistant bacteria can exceed 10 million annually, making it the leading cause of death. Conventional antibiotics are becoming less effective due to rapid bacterial drug resistance and slowed new antibiotic development, necessitating new strategies. Recently, materials with catalytic/enzymatic properties, known as nanozymes, have been developed, inspired by natural enzymes essential for bacterial eradication. Unlike recent literature reviews that broadly cover nanozyme design and biomedical applications, this review focuses on the latest advancements in nanozymes for combating bacterial drug resistance, emphasizing their design, structural characteristics, applications in combination therapy, and future prospects. This approach aims to promote nanozyme development for combating bacterial drug resistance, especially towards clinical translation.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanocluster Synthesis and Applications · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

The People's Hospital of Yuhuan Taizhou Zhejiang 317600 China

Department of International VIP Dental Clinic Tianjin Stomatological Hospital School of Medicine Nankai University Tianjin 300041 China

Tianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction Tianjin 300041 China

Translational Medicine Laboratory The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang 325035 China

State Key Laboratory of Medicinal Chemical Biology Nankai University Tianjin 300071 China

Funding

National Natural Science Foundation of China · Natural Science Foundation of Ningbo Municipality · Medical Science and Technology Project of Zhejiang Province

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