Transformative bioprinting: 4D printing and its role in the evolution of engineering and personalized medicine
Source abstract
Abstract
Transformative bioprinting, particularly 4D printing, is revolutionizing the field of biofabrication, offering dynamic solutions that respond to external stimuli. This paper explores the underlying mechanisms, materials, and stimuli that enable 4D printing to fabricate responsive and adaptive constructs. Section 1 delves into the foundational aspects of 4D bioprinting, detailing the stimuli-responsive materials, such as hydrogels and shape-memory polymers, and the mechanisms that drive their transformation. Additionally, the role of external factors, including temperature, pH, and magnetic or light-based stimuli, is analyzed to provide a comprehensive understanding of this evolving technology. Section 2 focuses on the diverse applications of 4D bioprinting, particularly in biomedical sciences. Key use cases include tissue engineering, drug delivery systems, and the creation of adaptive implants. Beyond healthcare, the potential for smart structures in fields like robotics and aerospace is highlighted, showcasing the technology's ability to deliver tailored, dynamic solutions across various domains. Section 3 categorizes additive manufacturing techniques relevant to 4D printing, offering an in-depth classification and comparison. This includes extrusion-based, vat polymerization, and inkjet printing technologies, emphasizing their compatibility with stimuli-responsive materials. Section 4 shifts focus to commercial advancements, presenting a classification of 4D bioprinters available in the market. The economic barriers, challenges in scalability, and ease of application for these printers are critically examined. Proposed solutions, such as innovative material sourcing, streamlined design strategies, and integration with AI for optimized performance, are presented to address these issues. This work provides a roadmap for integrating 4D bioprinting into scalable and cost-effective production, pushing the boundaries of biofabrication. It serves as a comprehensive guide for researchers and industries aiming to harness the transformative potential of 4D printing for adaptive and functional applications across various domains.
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Research context
OpenAlex topics: 3D Printing in Biomedical Research · Additive Manufacturing and 3D Printing Technologies · Innovative Microfluidic and Catalytic Techniques Innovation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Roopavath UK, Kalaskar DM. Introduction to 3D printing in medicine. In: Kalaskar DM, editor. 3D printing in medicine. Cambridge: Woodhead Publishing; 2017. p. 1–2010.1016/B978-0-08-100717-4.00001-6 ↗
2. Alemayehu DG, Zhang Z, Tahir E, Gateau D, Zhang DF, Ma X. Preoperative planning using 3D printing technology in orthopedic surgery. Biomed Res Int. 2021;2021(1):7940242.10.1155/2021/7940242 ↗
3. Eltorai AE, Nguyen E, Daniels AH. Three-dimensional printing in orthopedic surgery. Orthopedics. 2015;38(11):684–7.10.3928/01477447-20151016-05 ↗
4. Radenkovic D, Solouk A, Seifalian A. Personalized development of human organs using 3D printing technology. Med Hypotheses. 2016;87:30–3.10.1016/j.mehy.2015.12.017 ↗
5. Rider P, Kačarević ŽP, Alkildani S, Retnasingh S, Barbeck M. Bioprinting of tissue engineering scaffolds. J Tissue Eng. 2018;9:204.10.1177/2041731418802090 ↗
6. Gedam SS, Shahare HV. Regenerative medicine—A future medicine. Int J Pharm Bio Sci. 2010;1(1):34.
7. Eom TY. 3D Bioprinting technology in biochemical engineering. Korean Chem Eng Res. 2016;54(3):285–92.10.9713/kcer.2016.54.3.285 ↗
8. Huang Y, Li Q, Ye W, Huang Z, Qin H, Zhao M, et al. 4D bioprinting technology and its application in cardiovascular tissue engineering. Sheng Wu Gong Cheng Xue Bao. 2023;39(10):4046–56.
9. Shakibania S, Ghazanfari L, Raeeszadeh-Sarmazdeh M, Khakbiz M. Medical application of biomimetic 4D printing. Drug Dev Ind Pharm. 2021;47(4):521–34.10.1080/03639045.2020.1862179 ↗
10. Etawy MS, Nassar GE, Mohammed N, Nawar SH, Hassabo AG. 4D printing of stimuli-responsive materials. J Text Color Polym Sci. 2024;21(2):241–58.
11. Kumar P, Suryavanshi P, Dwivedy SK, Banerjee S. Stimuli-responsive materials for 4D printing: mechanical, manufacturing, and biomedical applications. J Mol Liq. 2024;125553.10.1016/j.molliq.2024.125553 ↗
12. Deng D, Kwok TH, Chen Y. Four-dimensional printing: design and fabrication of smooth curved surface using controlled self-folding. J Mech Des. 2017;139(8):081702.10.1115/1.4036996 ↗
13. Nelson TG, Avila A, Howell LL, Herder JL, Machekposhti DF. Origami-inspired sacrificial joints for folding compliant mechanisms. Mech Mach Theory. 2019;140:194–210.10.1016/j.mechmachtheory.2019.05.023 ↗
14. Lai J, Liu Y, Lu G, Yung P, Wang X, Tuan RS, Li ZA. 4D bioprinting of programmed dynamic tissues. Bioact Mater. 2024;37:348–77.
15. Tibbits S. 4D printing: multi-material shape change. Architectural Design. 2014;84(1):116–21.10.1002/ad.1710 ↗
16. Sydney Gladman A, Matsumoto EA, Nuzzo RG, Mahadevan L, Lewis JA. Biomimetic 4D printing. Nat Mater. 2016;15(4):413–8.10.1038/nmat4544 ↗
17. Ge Q, Sakhaei AH, Lee H, Dunn CK, Fang NX, Dunn ML. Multimaterial 4D printing with tailorable shape memory polymers. Sci Rep. 2016;6(1):31110.10.1038/srep31110 ↗
18. Kirillova A, Maxson R, Stoychev G, Gomillion CT, Ionov L. 4D biofabrication using shape-morphing hydrogels. Adv Mater. 2017;29(46):1703443.10.1002/adma.201703443 ↗
19. Ambulo CP, Burroughs JJ, Boothby JM, Kim H, Shankar MR, Ware TH. Four-dimensional printing of liquid crystal elastomers. ACS Appl Mater Interfaces. 2017;9(42):37332–9.10.1021/acsami.7b11851 ↗
20. Kuang X, Chen K, Dunn CK, Wu J, Li VCF, Qi HJ. 3D printing of highly stretchable, shape-memory, and self-healing elastomer toward novel 4D printing. ACS Appl Mater Interfaces. 2018;10(8):7381–8.10.1021/acsami.7b18265 ↗
21. Ding A, Jeon O, Cleveland D, Gasvoda K, Wells D, Lee SJ, et al. Jammed micro-flake hydrogel for 4D living cell bioprinting. Adv Mater. 2022;34(15):2109394.10.1002/adma.202109394 ↗
22. Chae S, Cho DW. Biomaterial-based 3D bioprinting strategy for orthopedic tissue engineering. Acta Biomater. 2023;156:4–20.10.1016/j.actbio.2022.08.004 ↗
23. Charbe NB, Zacconi FC, Amnerkar N, Pardhi D, Shukla P, Mukattash TL, et al. Emergence of three dimensional printed cardiac tissue: opportunities and challenges in cardiovascular diseases. Curr Cardiol Rev. 2019;15(3):188–204.10.2174/1573403X15666190112154710 ↗
24. Iqbal MH, Kerdjoudj H, Boulmedais F. Protein-based layer-by-layer films for biomedical applications. Chem Sci. 2024;15(25):9408–37.10.1039/D3SC06549A ↗
25. Sthijns MM, LaPointe VL, van Blitterswijk CA. Building complex life through self-organization. Tissue Eng Part A. 2019;25(19–20):1341–6.10.1089/ten.tea.2019.0208 ↗
26. Varadharajan S, Vasanthan KS, Agarwal P. Application of reversible four-dimensional printing of shape memory alloys and shape memory polymers in structural engineering: A state-of-the-art review. 3D Print Addit Manuf. 2024;11(3):919–53.10.1089/3dp.2022.0376 ↗
27. Parhi P, Golas A, Vogler EA. Role of proteins and water in the initial attachment of mammalian cells to biomedical surfaces: a review. J Adhes Sci Technol. 2010;24(5):853–88.10.1163/016942409X12598231567907 ↗
28. Iu E, Bogatch A, Plotnikov SV. Quantitative analysis of cell edge dynamics during cell spreading. J Vis Exp. 2021;171:e62369.
29. Mehrpouya M, Huang WM. Origami-inspired 4D printing. In: Smart materials in additive manufacturing. Amsterdam: Elsevier; 2022. p. 373–94.10.1016/B978-0-12-824082-3.00002-7 ↗
30. Arif ZU, Khalid MY, Ahmed W, Arshad H. A review on four-dimensional (4D) bioprinting in pursuit of advanced tissue engineering applications. Bioprinting. 2022;27:203.10.1016/j.bprint.2022.e00203 ↗
31. Rayate A, Jain PK. A review on 4D printing material composites and their applications. Mater Today Proc. 2018;5(9):20474–84.10.1016/j.matpr.2018.06.424 ↗
32. He Q, Okajima T, Onoe H, Subagyo A, Sueoka K, Kuribayashi-Shigetomi K. Origami-based self-folding of co-cultured NIH/3T3 and HepG2 cells into 3D microstructures. Sci Rep. 2018;8(1):4556.10.1038/s41598-018-22598-x ↗
33. Chadwick CM, et al. Rapid process drug evaluation glioblastoma patient-derived organoid model 4D bioprinted arrays. iScience. 2020;23(8):101365.10.1016/j.isci.2020.101365 ↗
34. Agarwal T, Chiesa I, Costantini M, Lopamarda A, Tirelli MC, Borra OP, Maiti TK. Chitosan and its derivatives in 3D/4D (bio) printing for tissue engineering and drug delivery applications. Int J Biol. Macromol 2023;246:125669.10.1016/j.ijbiomac.2023.125669 ↗
35. Mathur V, Agarwal P, Srinivasan V, Panwar A, Vasanthan KS. Facet of 4D printing in biomedicine. J Mater Res. 2023;38(1):2–18.10.1557/s43578-022-00779-9 ↗
36. Shie MY, Shen YF, Astuti SD, Lee AKX, Lin SH, Dwijaksara NLB, Chen YW. Review of polymeric materials in 4D printing biomedical applications. Polymers. 2019;11(11):1864.10.3390/polym11111864 ↗
37. Xin X, Lin C, Wang X, Liu F, Dong L, Liu L, et al. Dynamically customizable 4D printed shape memory polymer biomedical devices: a review. Mater Futures. 2024.10.1088/2752-5724/ad8898 ↗
38. Goya GF, Asín L, Ibarra MR. Cell death induced by ac magnetic fields and magnetic nanoparticles: current state and perspectives. Int J Hyperth. 2013;29(8):810–8. https://doi.org/10.3109/02656736.2013.838646.10.3109/02656736.2013.838646 ↗
39. Goodarzi Hosseinabadi H, Biswas A, Bhusal A, Yousefinejad A, Lall A, Zimmermann WH, et al. 4D‐printable photocrosslinkable polyurethane‐based inks for tissue scaffold and actuator applications. Small. 2024;20(6):2306387. https://doi.org/10.1002/smll.202306387.10.1002/smll.202306387 ↗
40. Zhou W, Qiao Z, Nazarzadeh Zare E, Huang J, Zheng X, Sun X, Shao M, Wang H, Wang X, Chen D, Zheng J. 4D-printed dynamic materials in biomedical applications: chemistry, challenges, and their future perspectives in the clinical sector. J Med Chem. 2020;63(15):8003–24. https://doi.org/10.1021/acs.jmedchem.9b02115.10.1021/acs.jmedchem.9b02115 ↗
41. Chung H, Das S. Processing and properties of glass bead particulate-filled functionally graded Nylon-11 composites produced by selective laser sintering. Mater Sci Eng A. 2006;437(2):226–34. https://doi.org/10.1016/j.msea.2006.07.112.10.1016/j.msea.2006.07.112 ↗
42. Lui YS, Sow WT, Tan LP, Wu Y, Lai Y, Li H. 4D printing and stimulus-responsive materials in biomedical aspects. Acta Biomater. 2019;92:19–36. https://doi.org/10.1016/j.actbio.2019.05.005.10.1016/j.actbio.2019.05.005 ↗
43. Tao R, Ji L, Li Y, Wan Z, Hu W, Wu W, Fang D. 4D printed origami metamaterials with tunable compression twist behavior and stress-strain curves. Compos Part B Eng. 2020;201:108344.10.1016/j.compositesb.2020.108344 ↗
44. Tao R, Xi L, Wu W, Li, Y, Liao B, Liu L, Fang, D 4D printed multistable metamaterials with mechanically tunable performance. Compos Struct. 2020;252:112663.10.1016/j.compstruct.2020.112663 ↗
45. Bodaghi M, Damanpack AR, Liao WH. Triple shape memory polymers by 4D printing. Smart Mater Struct. 2018;27(6):aabc2a. https://doi.org/10.1088/1361-665X/aabc2a.10.1088/1361-665X/aabc2a ↗
46. Jeong HY, Lee E, Ha S, Kim N, Jun YC. Multistable thermal actuators via multimaterial 4D printing. Adv Mater Technol. 2019;4(3):1–7. https://doi.org/10.1002/admt.201800495.10.1002/admt.201800495 ↗
47. Ali M, Alam F, Fah YF, Shiryayev O, Vahdati N, Butt H. 4D printed thermochromic Fresnel lenses for sensing applications. Compos Part B Eng. 2022;230:109514. https://doi.org/10.1016/j.compositesb.2021.109514.10.1016/j.compositesb.2021.109514 ↗
48. Chen H, Zhang J, Li Y, Liu X, Xu Z, et al. Bis-chalcone derivatives derived from natural products as near-UV/visible light sensitive photoinitiators for 3D/4D printing. Mater Chem Front. 2021;5(2):901–16. https://doi.org/10.1039/d0qm00755b.10.1039/d0qm00755b ↗
49. Hagaman DE, Leist S, Zhou J, Ji HF. Photoactivated polymeric bilayer actuators fabricated via 3D printing. ACS Appl Mater Interfaces. 2018;10(32):27308–15. https://doi.org/10.1021/acsami.8b08503.10.1021/acsami.8b08503 ↗
50. del Barrio J, Sánchez-Somolinos C. Light to shape the future: From photolithography to 4D printing. Adv Opt Mater. 2019;7(16):1900598. https://doi.org/10.1002/adom.201900598.10.1002/adom.201900598 ↗
51. Sheikh A, Abourehab MA, Kesharwani P. The clinical significance of 4D printing. Drug Discov Today. 2023;28(1):103391.10.1016/j.drudis.2022.103391 ↗
52. Shao LH, Zhao B, Zhang Q, Xing Y, Zhang K. 4D printing composite with electrically controlled local deformation. Extrem Mech Lett. 2020;39:100793. https://doi.org/10.1016/j.eml.2020.100793.10.1016/j.eml.2020.100793 ↗
53. Roy A, Hossain MS, Bhowmick A, Nizhum N, Kumar S. Prospects of 4D printing in pharmaceuticals. Pharmacologyonline. 2020;3:292-302
54. Sadeghi M, Soleimani F. Synthesis and characterization of superabsorbent hydrogels for oral drug delivery systems. Int J Chem Eng Appl. 2011;2(5):314–6. https://doi.org/10.7763/ijcea.2011.v2.125.10.7763/ijcea.2011.v2.125 ↗
55. Sharma K, Kumar V, Chaudhary B, Kaith BS, Kalia S, Swart HC. Application of biodegradable superabsorbent hydrogel composite based on Gum ghatti-co-poly(acrylic acid-aniline) for controlled drug delivery. Polym Degrad Stab. 2016;124:101–11. https://doi.org/10.1016/j.polymdegradstab.2015.12.021.10.1016/j.polymdegradstab.2015.12.021 ↗
56. Wu H, Zhang X, Ma Z, Zhang C, Ai, J, Chen P, Shi Y. A material combination concept to realize 4D printed products with newly emerging property/functionality. Adv Sci. 2020;7(9):1903208.10.1002/advs.201903208 ↗
57. Adam G, Benouhiba A, Rabenorosoa K, Clévy C, Cappelleri DJ. 4D printing: enabling technology for microrobotics applications. Adv Intell Syst. 2021;3(5):2000216. https://doi.org/10.1002/aisy.202000216.10.1002/aisy.202000216 ↗
58. Breger JC, Yoon C, Xiao R, Kwag HR, Wang MO, Fisher JP, Gracias DH. Self-folding thermo-magnetically responsive soft microgrippers. ACS Appl Mater Interfaces. 2015;7(5):3398–405.10.1021/am508621s ↗
59. Tamay DG, Usal TD, Alagoz AS, Yucel D, Hasirci N, Hasirci V. 3D and 4D printing of polymers for tissue engineering applications. Front Bioeng Biotechnol. 2019;7:164. https://doi.org/10.3389/fbioe.2019.00164.10.3389/fbioe.2019.00164 ↗
60. Schmaljohann D. Thermo- and pH-responsive polymers in drug delivery. Adv Drug Deliv Rev. 2006;58(15):1655–70. https://doi.org/10.1016/j.addr.2006.09.020.10.1016/j.addr.2006.09.020 ↗
61. Shang J, Theato P. Smart composite hydrogel with pH-, ionic strength- and temperature-induced actuation. Soft Matter. 2018;14(41):8401–7. https://doi.org/10.1039/c8sm01728j.10.1039/c8sm01728j ↗
62. Zhao S, Jia R, Yang J, Dai L, Ji N, Xiong L, Sun Q. Development of chitosan/tannic acid/corn starch multifunctional bilayer smart films as pH-responsive actuators and for fruit preservation. Int J Biol Macromol. 2022;205:419–29.10.1016/j.ijbiomac.2022.02.101 ↗
63. Placone JK, Duffy GP, Bhatia SN, et al. Development and characterization of a 3D printed, keratin-based hydrogel. Ann Biomed Eng. 2017;45(1):237–48. https://doi.org/10.1007/s10439-016-1621-7.10.1007/s10439-016-1621-7 ↗
64. He H, Guan J, Lee JL. An oral delivery device based on self-folding hydrogels. J Control Release. 2006;110(2):339–46. https://doi.org/10.1016/j.jconrel.2005.10.017.10.1016/j.jconrel.2005.10.017 ↗
65. Hu Y, Wang Z, Jin D, Zhang C, Sun R, Li Z, Chu J. Botanical-inspired 4D printing of hydrogel at the microscale. Adv Funct Mater. 2020;30(4):1907377.10.1002/adfm.201907377 ↗
66. Chu H, Yang W, Sun L, Cai S, Yang R, Liang W, Liu, L. 4D printing: a review on recent progresses. Micromachines. 2020;11(9):796.10.3390/mi11090796 ↗
67. Sahafnejad-Mohammadi I, Karamimoghadam M, Zolfagharian A, Akrami M, Bodaghi M. 4D printing technology in medical engineering: a narrative review. J Braz Soc Mech Sci Eng. 2022;44(6):1–26. https://doi.org/10.1007/s40430-022-03514-x.10.1007/s40430-022-03514-x ↗
68. Kim K, Guo Y, Bae J, Choi S, Song HY, Park S, Ahn SK. 4D printing of hygroscopic liquid crystal elastomer actuators. Small. 2021;17(23):202100910.10.1002/smll.202100910 ↗
69. Sol JAH, Smits LG, Schenning APHJ, Debije MG. Direct ink writing of 4D structural colors. Adv Funct Mater. 2022;32(30):2201766. https://doi.org/10.1002/adfm.20220176610.1002/adfm.202201766 ↗
70. Yu YJ, Hearon K, Wilson TS, Maitland DJ. The effect of moisture absorption on the physical properties of polyurethane shape memory polymer foams. Smart Mater Struct. 2011;20(8):085010. https://doi.org/10.1088/0964-1726/20/8/085010.10.1088/0964-1726/20/8/085010 ↗
71. De Haan LT, Verjans JMN, Broer DJ, Bastiaansen CWM, Schenning APHJ. Humidity-responsive liquid crystalline polymer actuators with an asymmetry in the molecular trigger that bend, fold, and curl. J Am Chem Soc. 2014;136(30):10585–8. https://doi.org/10.1021/ja505475x.10.1021/ja505475x ↗
72. Miriyev A, Stack K, Lipson H. Soft material for soft actuators. Nat Commun. 2017;8(1):685. https://doi.org/10.1038/s41467-017-00685-3.10.1038/s41467-017-00685-3 ↗
73. Guo B, Sun Y, Finne-Wistrand A, Mustafa K, Albertsson AC. Electroactive porous tubular scaffolds with degradability and non-cytotoxicity for neural tissue regeneration. Acta Biomater. 2012;8(1):144–53. https://doi.org/10.1016/j.actbio.2011.09.027.10.1016/j.actbio.2011.09.027 ↗
74. Elbaum R, Zaltzman L, Burgert I, Fratzl P. The role of wheat awns in the seed dispersal unit. Science. 2007;316(5826):884–6. https://doi.org/10.1126/science.1140097.10.1126/science.1140097 ↗
75. Agarwal P, Mathur V, Kasturi M, Srinivasan V, Seetharam RN, Vasanthan KS. A futuristic development in 3D printing technique using nanomaterials with a step toward 4D printing. ACS Omega. 2024;9(36):37445–58.10.1021/acsomega.4c04123 ↗
76. Augustine R. Skin bioprinting: a novel approach for creating artificial skin from synthetic and natural building blocks. Prog Biomater. 2018;7(2):77–92. https://doi.org/10.1007/s40204-018-0088-2.10.1007/s40204-018-0088-2 ↗
77. Hann SY, Cui H, Nowicki M, Zhang LG. 4D printing soft robotics for biomedical applications. Addit Manuf. 2020;36:101567. https://doi.org/10.1016/j.addma.2020.101567.10.1016/j.addma.2020.101567 ↗
78. Michael S, Sorg H, Peck CT, Koch L, Deiwick A, Chichkov B, et al. Tissue engineered skin substitutes created by laser-assisted bioprinting form skin-like structures in the dorsal skin fold chamber in mice. PLoS ONE. 2013;8(3):e57741. https://doi.org/10.1371/journal.pone.0057741.10.1371/journal.pone.0057741 ↗
79. Sorkio A, Koch L, Koivusalo L, Deiwick A, Miettinen S, Chichkov B, et al. Human stem cell-based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks. Biomaterials. 2018;171:57–71.10.1016/j.biomaterials.2018.04.034 ↗
80. Nakamura M, Henmi C. 3D micro-fabrication by inkjet 3D biofabrication for 3D tissue engineering. In: Proceedings of the 2008 International Symposium on Micro-NanoMechatronics and Human Science; 2008 Nov 9–12; Nagoya, Japan. IEEE; 2008. p. 451–6.10.1109/MHS.2008.4752495 ↗
81. Vaezi M, Yang S. Freeform fabrication of nanobiomaterials using 3D printing. In: Rapid Prototyping of Biomaterials. Woodhead Publishing; 2014. p. 41–92.10.1016/B978-0-08-102663-2.00003-4 ↗
82. Murphy SV, Atala A. 3D bioprinting of tissues and organs. Nat Biotechnol. 2014;32(8):773–85.10.1038/nbt.2958 ↗
83. Ker ED, Nain AS, Weiss LE, Wang J, Suhan J, Amon CH, Campbell PG. Bioprinting of growth factors onto aligned submicron fibrous scaffolds for simultaneous control of cell differentiation and alignment. Biomaterials. 2011;32(32):8097–107.10.1016/j.biomaterials.2011.07.025 ↗
84. Jia C, Luo B, Wang H, Bian Y, Li X, Li S, Wang H. Precise and arbitrary deposition of biomolecules onto biomimetic fibrous matrices for spatially controlled cell distribution and functions. Adv Mater. 2017;29(35):1701154.10.1002/adma.201701154 ↗
85. Cooper GM, Miller ED, DeCesare GE, Usas A, Lensie EL, Bykowski MR, Huard J, Weiss LE, Losee JE, Campbell PG. Inkjet-based biopatterning of bone morphogenetic protein-2 to spatially control calvarial bone formation. Tissue Eng Part A. 2010;16(5):1749–59.10.1089/ten.tea.2009.0650 ↗
86. Smith DM, Cray JJ Jr, Weiss LE, Dai Fei EK, Shakir S, Rottgers SA, Losee JE, Campbell PG, Cooper GM. Precise control of osteogenesis for craniofacial defect repair: the role of direct osteoprogenitor contact in BMP-2-based bioprinting. Ann Plast Surg. 2012;69:485–8.10.1097/SAP.0b013e31824cfe64 ↗
87. Saunders RE, Derby B. Inkjet printing biomaterials for tissue engineering: bioprinting. Int Mater Rev. 2014;59(8):430–48.10.1179/1743280414Y.0000000040 ↗
88. Duarte Campos DF, Rohde M, Ross M, Anvari P, Blaeser A, Vogt M, Panfil C, Yam GH-F, Mehta JS, Fischer H, Walter P, Fuest M. Corneal bioprinting utilizing collagen-based bioinks and primary human keratocytes. J Biomed Mater Res Part A. 2019;107(9):1945–53.10.1002/jbm.a.36702 ↗
89. Wu Z, Su X, Xu Y, Kong B, Sun W, Mi S. Bioprinting three-dimensional cell-laden tissue constructs with controllable degradation. Sci Rep. 2016;6:1–10.10.1038/s41598-016-0001-8 ↗
90. Kolesky DB, Truby RL, Gladman AS, Busbee TA, Homan KA, Lewis JA. 3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs. Adv Mater. 2014;26(19):3124–30.10.1002/adma.201305506 ↗
91. Mu T, Liu L, Lan X, Liu Y, Leng J. Shape memory polymers for composites. Compos Sci Technol. 2018;160:169–98. https://doi.org/10.1016/j.compscitech.2018.03.018.10.1016/j.compscitech.2018.03.018 ↗
92. Senatov FS, et al. Shape memory effect in 3D-printed scaffolds for self-fitting implants. Eur Polym J. 2017;93:222–321. https://doi.org/10.1016/j.eurpolymj.2017.06.011.10.1016/j.eurpolymj.2017.06.011 ↗
93. Shin DG, Kim TH, Kim DE. Review of 4D printing materials and their properties. Int J Precis Eng Manuf - Green Technol. 2017;4(3):349–57. https://doi.org/10.1007/s40684-017-0040-z.10.1007/s40684-017-0040-z ↗
94. Pilate F, Toncheva A, Dubois P, Raquez JM. Shape-memory polymers for multiple applications in the materials world. Eur Polym J. 2016;80:268–94. https://doi.org/10.1016/j.eurpolymj.2016.05.004.10.1016/j.eurpolymj.2016.05.004 ↗
95. Leist SK, Zhou J. Current status of 4D printing technology and the potential of light-reactive smart materials as 4D printable materials. Virtual Phys Prototyp. 2016;11(4):249–62. https://doi.org/10.1080/17452759.2016.1198630.10.1080/17452759.2016.1198630 ↗
96. Invernizzi M, Turri S, Levi M, Suriano R. 4D printed thermally activated self-healing and shape memory polycaprolactone-based polymers. Eur Polym J. 2018;101:169–76. https://doi.org/10.1016/j.eurpolymj.2018.02.023.10.1016/j.eurpolymj.2018.02.023 ↗
97. Zotzmann J, Behl M, Hofmann D, Lendlein A. Reversible triple-shape effect of polymer networks containing polypentadecalactone- and poly(ε-caprolactone)-segments. Adv Mater. 2010;22(31):3424–9. https://doi.org/10.1002/adma.200904202.10.1002/adma.200904202 ↗
98. Kang M, Pyo Y, young Jang J, Park Y, Son YH, Choi M, Lee CS. Design of a shape memory composite (SMC) using 4D printing technology. Sens Actuators A Phys. 2018;283:187–95.10.1016/j.sna.2018.08.049 ↗
99. Wu JJ, Huang LM, Zhao Q, Xie T. 4D printing: history and recent progress. Chin J Polym Sci. 2018;36(5):563–75. https://doi.org/10.1007/s10118-018-2089-8.10.1007/s10118-018-2089-8 ↗
100. Ahmed K, Shiblee MNI, Khosla A, Nagahara L, Thundat T, Furukawa H. Recent progresses in 4D printing of gel materials. J Electrochem Soc. 2020;167(3):037563. https://doi.org/10.1149/1945-7111/ab6e60.10.1149/1945-7111/ab6e60 ↗