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Intelligent prediction of thermodynamic performance in MHD Oldroyd B trihybrid nanofluids using artificial neural networks

Mamoon Aamir, Chemseddine Maatki, Aqsa Zafar Abbasi, Rajab Alsayegh et al.

This research aims to describe the flow characteristics and entropy creation of an Oldroyd-B tri hybrid nanofluid under conditions of MHD with heat transfer through a hybrid numerical-machine learning framework. The nonlinear boundary layer governing equations for momentum and heat transport are transformed to a commonly used ordinary differential equations (ODE) form via simil…

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The internalization of three types of carbon nanoparticles by HeLa cells in vitro

Lan Sun, Fei Peng, Bao-Quan Zhao, Hao Zhang et al.

Introduction We have found activated carbon nanoparticles (ACNP) can be used as carriers of nanodrug delivery systems to treat cervical cancer. But how ACNP to enter into the HeLa cell, how to distribute, translocate and, metabolize and develop therapeutic effects has been unknown. In this paper, we invested the action of ACNP on HaLa cells in comparison with single walled carb…

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Disease mechanisms and translational barriers guide nanocarrier design for nose to brain delivery in Alzheimer’s disease

Chenqi Liao, Danyang Sun, Xiong Wang

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited disease-modifying treatment options, partly because many therapeutic agents show insufficient brain exposure and dose-limiting systemic adverse effects after conventional administration. Nose-to-brain (N2B) delivery has emerged as a non-invasive strategy to transport therapeutics to the central ne…

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Mechanical insights into regulation of bio–nano interactions for lipid-based nanocarriers

Fan Yang, Yikai Wang, Yuhan Lu, Lin Lin et al.

Lipid nanocarriers (LNCs), including liposomes, lipid nanoparticles (LNPs), and extracellular vesicles (EVs), are promising platforms for targeted drug delivery. However, their clinical translation is hindered by multi-level heterogeneity and complex behaviors at the bio-nano interface. Interest in mechanotargeted delivery strategies has grown rapidly, as the mechanical propert…

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Numerical investigation of heat and mass transfer in radiative micropolar Sutterby nanofluid flow with activation energy through a porous stretching sheet

Muhammad Jawad, Muhammad Waseem, Walid Abdelfattah, Tadesse Walelign et al.

In engineering and technology, the micropolar-Sutterby fluid serves as a favorable alternative to conventional non-Newtonian fluids due to its practical applicability, robustness, and computational efficiency. This analysis focuses on the thermophysical characteristics of the magnetized flow of a micropolar-Sutterby fluid bounded by an exponentially stretching surface, taking i…

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Formulation and characterization of nano biopesticides via nanosuspension technology and its packaging designs

XiaoPeng Niu, Yue Shen, Pei Wang, Kousar Rasheed

Pesticides have long been essential in agriculture for controlling pests, diseases, and weeds; however, their extensive use has led to serious concerns regarding resistance development, environmental contamination, and human health risks. Nano-biopesticides have emerged as a sustainable alternative, offering enhanced efficacy, reduced toxicity, improved target specificity, and …

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Zinc oxide/copper ferrite ferrofluids derived from natural resources for antifungal applications

Febriana Rahmawati, Yap Wing Fen, ST. Ulfawanti Intan Subadra, Nurul Hidayat et al.

Abstract One of the serious global health issues is related to toxigenic fungi, especially Aspergillus flavus . To address this issue, it is crucial to develop eco-friendly and effective antifungal agents. Therefore, we develop zinc oxide/copper ferrite–soursop leaf extract nanocomposites as novel antifungal agents using a combination of sol–gel, coprecipitation, and mixing met…

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Discover Nano·2026Open access
Synthesis, characterisation and electrochemical behaviour of calcium carbonate nanoparticles derived from automobile oxy-acetylene gas welding waste

Nnabuk Okon Eddy, Sunday Nweze, Ifeanyi Samson Eze, Rajni Garg et al.

In actualizing the management of this toxic waste, resource recovery was designed to convert the Ca(OH) 2 rich waste (generated by automobile welding process) to calcium carbonate nanoparticles (CaCO 3 NPs). The synthesized nanoparticles were characterized using XRF, SEM–EDX, XRD, FTIR, XPS, TGA/DTA, BET, DFT and EIS. Results from XRF and SEM–EDX analyses showed calcium as the …

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Discover Nano·2026Open access
Empowering nanoscale heat transfer using ecofriendly quint nanomaterial powered by response surface technique (RST) and ANOVA scheme coupled with radiation effects

Adnan, Dase Fayera Hule, S. U. Khan, Mustafa Abdullah et al.

PURPOSE: The key purpose of this research is to analyze the heat transfer in dovetail device wetted with quint nanofluid subject to different influential parameters like radiations, porosity, convective, conductive, heat generation and their contribution in the heat transfer. Further, to investigate the joint effects of linear and nonlinear heating sources. DESIGN/METHODOLOGY/A…

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Discover Nano·2026Open access
Simulation of oxytactic microbes in hybrid nanofluid with activation energy and LTNE effects using Bayesian regularization neural network technique

Munawar Abbas, Md. Mahbub Alam, Mohamed Bechir Ben Hamida, Murad Khan Hassani

This model has significant applications in advanced thermal and bioengineering systems where coupled fluid flow, heat transport, and microbial dynamics are vital. It is applicable to the design of bioreactors and microbial fuel cells, where Oxytactic bacteria improve mixing and mass transfer efficiency. The model optimizes heat transport in nanofluid-based cooling systems, part…

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Discover Nano·2026Open access
Entropy generation and response surface analysis of tri-hybrid casson nanofluid with nonlinear radiation over a rotating disk

Priyanka Pavuldass, P. Bala Anki Reddy

Trihybrid nanofluids possess promising applications in the biomedical, electronic, cosmetic, and materials processing fields owing to their enhanced thermophysical characteristics. This study examined the flow and thermal characteristics of a tri-hybrid ([Formula: see text])/blood Casson nanofluid over a rotating disk, influenced by nonlinear thermal radiation, focusing on the …

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Discover Nano·2026Open access
Hybrid Z‑scan simultaneously probes nonlinear absorption and fluorescence competition in xanthene dye systems with plasmonic nanoparticles

Soheil Sharifi

A hybrid Z-scan setup with a grating spectrometer and CCD capable of recording light transmission, fluorescent intensity, and elastic scattering is designed to study five xanthene dyes such as Rose Bengal, Rhodamine B, Rhodamine 6G, Eosin-B, and Erythrosine-B mixed with citrate-stabilized silver and platinum nanoparticles. Fluorescence and light scattering recorded at two posit…

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Discover Nano·2026Open access
Green synthesized cobalt doped graphene quantum dots derived from Boswellia serrata for dual ligand targeted bioimaging and delivery of exemestane

Minal T. Harde, Rahul Ingle, Sakshi Dhamal, Prashant Deshmukh et al.

Major objective of hydrothermal method is to achieve the synthesis of Cobalt doped Graphene quantum dots (Co-GQDs) using natural precursor (Boswellia serrata gum resin). The Co-GQDs were surface engineered with folic acid (FA) and hyaluronic acid (HA) to enable dual targeting module (Co-GQDFH), followed by loading of the anticancer drug Exemestane (EXE@Co-GQDs). The nanosized, …

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Discover Nano·2026Open access
Numerical optimization of laser radius ratio and power in photothermal therapy of various ellipsoidal tumor shape

Hyeongyoon Choi, Uijin Oh, Donghyuk Kim, Hyunjung Kim

Cancer remains a major global health burden, and the incidence of skin cancer has steadily increased over the past several decades. Among various treatment modalities, photothermal therapy (PTT), a noninvasive technique, has attracted considerable attention due to its advantages of minimal bleeding and rapid recovery. Although extensive research on PTT has been conducted, most …

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Discover Nano·2026Open access
Marangoni convection MHD flow of hybrid nanofluid in a saturated porous medium

Waqas Ahmad, Muhammad Saqib, Ilyas Khan, Tareq Alqahtani et al.

To enhance the productivity of heat exchangers, a new type of heat transfer fluid called hybrid nanofluid was characterized. An abundance of industrial and technological processes depends on heat transfer through these fluid flows, whether in laminar or turbulent conditions. The thermal resistance of the fluid based on a heat transfer system might be increased to improve a sign…

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Discover Nano·2026Open access
Systematic evaluation and statistical modeling of dual centrifugation and high-pressure homogenization as promising methods for scalable preparation of polymeric nanoparticles

Amr Ehab Kamel, Stefanie Klein, Lisa Schöne, Sara Gabr et al.

Nanobiomaterials have emerged as critical platforms for modern therapeutics, offering targeted delivery, controlled release, and improved performance. Among these, polymeric PLGA nanoparticles (PLGA-NPs) are widely studied due to their tailorability, biocompatibility, biodegradability, and regulatory acceptance. However, their clinical translation depends on robust manufacturin…

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Discover Nano·2026Open access
Smart nanoparticle vaccines integrate nanotechnology artificial intelligence and immunoengineering for precision immunization

Iman Morshedi, Zahra Roodaki, Pejman Gheibi, Ghazal Zamani et al.

The rise of multidrug-resistant microbes, rapidly evolving viruses, and recurring pandemics underscores the urgent need for advanced vaccine technologies. Nanoparticle-based vaccines have emerged as a transformative approach capable of overcoming the major shortcomings of traditional immunization methods. Their nanoscale architecture allows precise antigen targeting, enhanced s…

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Discover Nano·2026Open access
Machine learning based prediction of Williamson–Casson fluid flow with Cattaneo–Christov heat transfer over a curved stretching sheet

Ebrahem A. Algehyne, I. A. A. Manahill, Mohammed Rabih, Fahad Maqbul Alamrani et al.

Accurate prediction of non-Newtonian nanofluid flow and heat transfer under melting heat conditions is essential for applications in advanced thermal management systems, polymer extrusion and coating processes, metallurgical melting operations, biomedical fluid transport, micro- and nano-scale heat exchangers, and energy systems. Motivated by these practical applications, the c…

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Discover Nano·2026Open access
Nanomaterial toxicity and risk assessment integrating functionalization strategies advanced in vitro models and regulatory perspectives

Jitendra Patel, Harekrishna Roy, Deepak S. Khobragade, Nihar Ranjan Das et al.

Nanomaterials have gained huge importance in various fields, such as healthcare, electronics, and environmental management, due to their unique characteristics. However, the potent toxicity is a big concern regarding their utility. Toxicological assessment becomes an important step to ensure their safe applications. The significant hazards of nanomaterials have risen from their…

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Discover Nano·2026Open access
Cationic carbon dot–silver nanohybrids with enhanced stability and redox control

Nicolás Santos, Javier Muñoz, Marco Soto-Arriaza, Carlos Jara-Gutiérrez et al.

Silver nanoparticles (AgNPs) show promise for biomedical applications, but their functional stability remains a major challenge. Here, the photochemical synthesis of hybrid AgNPs using carbon dots (CDs) as both reducing and capping agents (CDs-AgNPs) is described, producing highly stable nanostructures under physiological conditions. Comparisons with traditionally synthesized A…

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