From nature to nanomedicine: bioengineered metallic nanoparticles bridge the gap for medical applications
Source abstract
Abstract
Abstract The escalating global challenge of antimicrobial resistance demands innovative approaches. This review delves into the current status and future prospects of bioengineered metallic nanoparticles derived from natural sources as potent antimicrobial agents. The unique attributes of metallic nanoparticles and the abundance of natural resources have sparked a burgeoning field of research in combating microbial infections. A systematic review of the literature was conducted, encompassing a wide range of studies investigating the synthesis, characterization, and antimicrobial mechanisms of bioengineered metallic nanoparticles. Databases such as PubMed, Scopus, Web of Science, ScienceDirect, Springer, Taylor & Francis online and OpenAthen were extensively searched to compile a comprehensive overview of the topic. The synthesis methods, including green and sustainable approaches, were examined, as were the diverse biological sources used in nanoparticle fabrication. The amalgamation of metallic nanoparticles and natural products has yielded promising antimicrobial agents. Their multifaceted mechanisms, including membrane disruption, oxidative stress induction, and enzyme inhibition, render them effective against various pathogens, including drug-resistant strains. Moreover, the potential for targeted drug delivery systems using these nanoparticles has opened new avenues for personalized medicine. Bioengineered metallic nanoparticles derived from natural sources represent a dynamic frontier in the battle against microbial infections. The current status of research underscores their remarkable antimicrobial efficacy and multifaceted mechanisms of action. Future prospects are bright, with opportunities for scalability and cost-effectiveness through sustainable synthesis methods. However, addressing toxicity, regulatory hurdles, and environmental considerations remains crucial. In conclusion, this review highlights the evolving landscape of bioengineered metallic nanoparticles, offering valuable insights into their current status and their potential to revolutionize antimicrobial therapy in the future. Graphical Abstract
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Graphene and Nanomaterials Applications · Nanoparticle-Based Drug Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Rai M, Ingle AP, Birla S, Yadav A, Santos CAD. Strategic role of selected noble metal nanoparticles in medicine. Crit Rev Microbiol. 2016;42(5):696–719. https://doi.org/10.3109/1040841X.2015.1018131.10.3109/1040841X.2015.1018131 ↗
2. Khorsandi K, Hosseinzadeh R, Esfahani HS, SaeedehKeyvani-Ghamsari & Saeed Ur Rahman,. Nanomaterials as drug delivery systems with antibacterial properties: current trends and future priorities. Expert Rev Anti Infect Ther. 2021;19(10):1299–323. https://doi.org/10.1080/14787210.2021.1908125.10.1080/14787210.2021.1908125 ↗
3. Agreles MAA, Cavalcanti IDL, Cavalcanti IMF. Synergism between metallic nanoparticles and antibiotics. Appl Microbiol Biotechnol. 2022;106(11):3973–84. https://doi.org/10.1007/s00253-022-12001-1. (Epub 2022 Jun 7 PMID: 35670851).10.1007/s00253-022-12001-1 ↗
4. Sharma D, Gulati SS, Sharma N, et al. Correction to: sustainable synthesis of silver nanoparticles using various biological sources and waste materials: a review. Emergent Mater. 2022;5:1167. https://doi.org/10.1007/s42247-021-00316-0.10.1007/s42247-021-00316-0 ↗
5. Majeed S, Saravanan M, Danish M, Zakariya NA, Ibrahim MN, Rizvi EH, un Nisa Andrabi S, Barabadi H, Mohanta YK, Mostafavi E. Bioengineering of green-synthesized TAT peptide-functionalized silver nanoparticles for apoptotic cell-death mediated therapy of breast adenocarcinoma. Talanta. 2023;253:124026. https://doi.org/10.1016/j.talanta.2022.124026.10.1016/j.talanta.2022.124026 ↗
6. Xu S, Zhang F, Yao L, et al. Eco-friendly fabrication of antibacterial cotton fibers by the cooperative self-assembly of hyperbranched poly(amidoamine)- and hyperbranched poly(amine-ester)-functionalized silver nanoparticles. Cellulose. 2017;24:1493–509. https://doi.org/10.1007/s10570-016-1178-5.10.1007/s10570-016-1178-5 ↗
7. Maddiboyina BR, Nakkala RK, Roy H. Perspectives on cutting-edge nanoparticulate drug delivery technologies based on lipids and their applications. Chem Biol Drug Des. 2023;102(2):377–94.10.1111/cbdd.14230 ↗
8. Maddiboyina B, Roy H, Nakkala RK, Gandhi S, Kavisri M, Moovendhan M. Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application. Chem Biol Drug Des. 2023;102(3):457–70. https://doi.org/10.1111/cbdd.14222. (Epub 2023 Mar 14 PMID: 36856306).10.1111/cbdd.14222 ↗
9. Roy H, Panda SP, Panda SK, Tripathi AK, Srivastava SK, Nayak BS, Singh PK, Singh GD. N-trimethyl chitosan and tripalmitin loaded solid lipid nanoparticles of tofacitinib citrate: characterization and in-vivo anti-inflammatory assessment. J Drug Delivery Sci Technol. 2023. https://doi.org/10.1016/j.jddst.2023.104789.10.1016/j.jddst.2023.104789 ↗
10. Krishnamoorthy S, Zait NN, Nasir AM, Ishar SM, Hamzah NH, RusDin RD, Osman K. Towards development of green nanoparticles in applied health application: A mini review. Mater Today Proc. 2023. https://doi.org/10.1016/j.matpr.2023.02.022.10.1016/j.matpr.2023.02.022 ↗
11. Sarip NA, Aminudin NI, Danial WH. Green synthesis of metal nanoparticles using Garcinia extracts: a review. Environ Chem Lett. 2021. https://doi.org/10.1007/s10311-021-01319-3.10.1007/s10311-021-01319-3 ↗
12. Alahdal FAM, Qashqoosh MTA, Manea YK, Mohammed RKA, Naqvi S. Green synthesis and characterization of copper nanoparticles using phragmantheraaustroarabica extract and their biological/environmental applications. Sustain Mater Technol. 2023. https://doi.org/10.1016/j.susmat.2022.e00540.10.1016/j.susmat.2022.e00540 ↗
13. Benedec D, IlioaraOniga FC, Sevastre B, Stiufiuc G, Duma M, Hanganu D, Iacovita C, RaresStiufiuc & Constantin Mihai Lucaciu,. Origanum vulgare mediated green synthesis of biocompatible gold nanoparticles simultaneously possessing plasmonic, antioxidant and antimicrobial properties. Int J Nanomed. 2018;13:1041–58. https://doi.org/10.2147/IJN.S149819.10.2147/IJN.S149819 ↗
14. Shejawal KP, Randive DS, Bhinge SD, Bhutkar MA, Wadkar GH, Jadhav NR. Green synthesis of silver and iron nanoparticles of isolated proanthocyanidin: its characterization, antioxidant, antimicrobial, and cytotoxic activities against COLO320DM and HT29. J Genet EngBiotechnol. 2020;18(1):43. https://doi.org/10.1186/s43141-020-00058-2.10.1186/s43141-020-00058-2 ↗
15. Kamaraj C, Ragavendran C, Manimaran K, Sarvesh S, Islam ARMT, Malafaia G. Green synthesis of silver nanoparticles from cassia auriculata: Targeting antibacterial, antioxidant activity, and evaluation of their possible effects on saltwater microcrustacean, artemia nauplii (non-target organism). Sci Total Environ. 2023. https://doi.org/10.1016/j.scitotenv.2022.160575.10.1016/j.scitotenv.2022.160575 ↗
16. Asong JA, Frimpong EK, Seepe HA, Katata-Seru L, Amoo SO, Aremu AO. Green synthesis of characterized silver nanoparticle using cullen tomentosum and assessment of its antibacterial activity. Antibiotics (Basel). 2023;12(2):203. https://doi.org/10.3390/antibiotics12020203.PMID:36830116;PMCID:PMC9952626.10.3390/antibiotics12020203.PMID:36830116;PMCID:PMC9952626 ↗
17. Shaaban MT, Zayed M, Salama HS. Antibacterial potential of bacterial cellulose impregnated with green synthesized silver nanoparticle against S. aureus and P. aeruginosa. Curr Microbiol. 2023;80:75. https://doi.org/10.1007/s00284-023-03182-7.10.1007/s00284-023-03182-7 ↗
18. Ajlouni A, Hamdan EH, Alshalawi RAE, Shaik MR, Khan M, Kuniyil M, Adil SF. Green synthesis of silver nanoparticles using aerial part extract of the anthemis pseudocotulaboiss plant and their biological activity. Molecules. 2023. https://doi.org/10.3390/molecules28010246.10.3390/molecules28010246 ↗
19. Paul A, Roychoudhury A. Go green to protect plants: repurposing the antimicrobial activity of biosynthesized silver nanoparticles to combat phytopathogens. Nanotechnol Environ Eng. 2021;6:10. https://doi.org/10.1007/s41204-021-00103-6.10.1007/s41204-021-00103-6 ↗
20. Peralta-Videa JR, Huang Y, Parsons JG, et al. Plant-based green synthesis of metallic nanoparticles: scientific curiosity or a realistic alternative to chemical synthesis? Nanotechnol Environ Eng. 2016;1:4. https://doi.org/10.1007/s41204-016-0004-5.10.1007/s41204-016-0004-5 ↗
21. Singh J, Dutta T, Kim KH, et al. ‘Green’ synthesis of metals and their oxide nanoparticles: applications for environmental remediation. J Nanobiotechnol. 2018;16:84. https://doi.org/10.1186/s12951-018-0408-4.10.1186/s12951-018-0408-4 ↗
22. Park Y. A new paradigm shift for the green synthesis of antibacterial silver nanoparticles utilizing plant extracts. Toxicol Res. 2014;30:169–78. https://doi.org/10.5487/TR.2014.30.3.169.10.5487/TR.2014.30.3.169 ↗
23. Aswathi VP, Meera S, Maria CGA, et al. Green synthesis of nanoparticles from biodegradable waste extracts and their applications: a critical review. Nanotechnol Environ Eng. 2022. https://doi.org/10.1007/s41204-022-00276-8.10.1007/s41204-022-00276-8 ↗
24. Gudimalla A, Jose J, Varghese R, et al. Green synthesis of silver nanoparticles using nymphae odorata extract incorporated films and antimicrobial activity. J Polym Environ. 2021;29:1412–23. https://doi.org/10.1007/s10924-020-01959-6.10.1007/s10924-020-01959-6 ↗
25. Gaikwad S, Torane R, Parthibavarman M. Cassia fistula-assisted green synthesis, characterization and their antimicrobial activity of zinc oxide ZnO nanomaterial’s an intracanal microbial agent on oral dental caries. Nanotechnol Russia. 2020;15:760–9. https://doi.org/10.1134/S199507802006021X.10.1134/S199507802006021X ↗
26. Rajoriya P, Barcelos MCS, Ferreira DCM, et al. Green silver nanoparticles: recent trends and technological developments. J Polym Environ. 2021;29:2711–37. https://doi.org/10.1007/s10924-021-02071-z.10.1007/s10924-021-02071-z ↗
27. Sameena VP, Thoppil JE. Green synthesis of silver nanoparticles from Euphorbia and its biological activities. Nanotechnol Environ Eng. 2022;7:377–92. https://doi.org/10.1007/s41204-022-00232-6.10.1007/s41204-022-00232-6 ↗
28. Barabadi H, Mobaraki K, Ashouri F, Noqani H, Jounaki K, Mostafavi E. Nanobiotechnological approaches in antinociceptive therapy: animal-based evidence for analgesic nanotherapeutics of bioengineered silver and gold nanomaterials. Adv Coll Interface Sci. 2023;2: 102917. https://doi.org/10.1016/j.cis.2023.102917.10.1016/j.cis.2023.102917 ↗
29. Barabadi H, Jounaki K, Pishgahzadeh E, Morad H, Sadeghian-Abadi S, Vahidi H, Hussain CM. Antiviral potential of green-synthesized silver nanoparticles. In: Handbook of Microbial Nanotechnology 2022 Jan 1 (pp. 285–310). Academic Press. https://doi.org/10.1016/B978-0-12-823426-6.00030-910.1016/B978-0-12-823426-6.00030-9 ↗
30. Barabadi H, Noqani H, Ashouri F, Prasad A, Jounaki K, Mobaraki K, Mohanta YK, Mostafavi E. Nanobiotechnological approaches in anticoagulant therapy: the role of bioengineered silver and gold nanomaterials. Talanta. 2023;1(256): 124279. https://doi.org/10.1016/j.talanta.2023.124279.10.1016/j.talanta.2023.124279 ↗
31. Hatipoğlu A, Baran A, Keskin C, et al. Green synthesis of silver nanoparticles based on the Raphanus sativus leaf aqueous extract and their toxicological/microbiological activities. Environ Sci Pollut Res. 2023. https://doi.org/10.1007/s11356-023-26499-z.10.1007/s11356-023-26499-z ↗
32. Tahir A, Quispe C, Herrera-Bravo J, et al. Green synthesis, characterization and antibacterial, antifungal, larvicidal and anti-termite activities of copper nanoparticles derived from Grewia asiatica L. Bull Natl Res Cent. 2022;46:188. https://doi.org/10.1186/s42269-022-00877-y.10.1186/s42269-022-00877-y ↗
33. Skiba M, Vorobyova V. Green synthesis and characterization of silver nanoparticles using Prunus persica L. (peach pomace) with natural deep eutectic solvent and plasma-liquid process. Chem Pap. 2022;76:5789–806. https://doi.org/10.1007/s11696-022-02274-1.10.1007/s11696-022-02274-1 ↗
34. Karthik C, Punnaivalavan KA, Prabha SP, et al. Multifarious global flora fabricated phytosynthesis of silver nanoparticles: a green nanoweapon for antiviral approach including SARS-CoV-2. Int Nano Lett. 2022;12:313–44. https://doi.org/10.1007/s40089-022-00367-z.10.1007/s40089-022-00367-z ↗
35. Jayappa MD, Ramaiah CK, Kumar MAP, et al. Green synthesis of zinc oxide nanoparticles from the leaf, stem and in vitro grown callus of Mussaendafrondosa L. characterization and their applications. Appl Nanosci. 2020;10:3057–74. https://doi.org/10.1007/s13204-020-01382-2.10.1007/s13204-020-01382-2 ↗
36. Ijaz M, Zafar M, Iqbal T. Green synthesis of silver nanoparticles by using various extracts: a review. Inorganic Nano-Metal Chem. 2021;51(5):744–55. https://doi.org/10.1080/24701556.2020.1808680.10.1080/24701556.2020.1808680 ↗
37. Simon S, Sibuyi NRS, OluwaseunFadaka A, Meyer M, MadimabeMadiehe A, Geraldine M, du Preez,. The antimicrobial activity of biogenic silver nanoparticles synthesized from extracts of Red and Green European pear cultivars. Artif Cells Nanomed Biotechnol. 2021;49(1):613–24. https://doi.org/10.1080/21691401.2021.1980884.10.1080/21691401.2021.1980884 ↗
38. MasudRahamanMollick Md, BiplabBhowmick DipanwitaMaity, Mondal D, Bain MK, Bankura K, Sarkar J, Rana D, Acharya K, Chattopadhyay D. Green synthesis of silver nanoparticles using Paederiafoetida L. leaf extract and assessment of their antimicrobial activities. Int J Green Nanotechnol. 2012;4(3):230–9. https://doi.org/10.1080/19430892.2012.706103.10.1080/19430892.2012.706103 ↗
39. Singh P, Kim YJ, Wang C, Ramya Mathiyalagan&Deok C. Yang,. Weissellaoryzae DC6-facilitated green synthesis of silver nanoparticles and their antimicrobial potential. Artif Cells Nanomed Biotechnol. 2016;44(6):1569–75. https://doi.org/10.3109/21691401.2015.1064937.10.3109/21691401.2015.1064937 ↗
40. Nadeem M, Khan R, Afridi K, Nadhman A, Ullah S, Faisal S, UlMabood Z, Hano C, Abbasi BH. Green synthesis of cerium oxide nanoparticles (CeO2 NPs) and their antimicrobial applications: a review. Int J Nanomed. 2020;15:5951–61. https://doi.org/10.2147/IJN.S255784.10.2147/IJN.S255784 ↗
41. Rónavári A, DávidKovács NóraIgaz, Vágvölgyi C, ImreMiklósBoros ZK, Pfeiffer I, MónikaKiricsi,. Biological activity of green-synthesized silver nanoparticles depends on the applied natural extracts: a comprehensive study. Int J Nanomed. 2017;12:871–83. https://doi.org/10.2147/IJN.S122842.10.2147/IJN.S122842 ↗
42. Salem MZM, EL-Hefny, M., Ali, H. M., Abdel-Megeed, A., El-Settawy, A. A. A., Böhm, M., Salem, A. Z. M. Plants-derived bioactives: Novel utilization as antimicrobial, antioxidant and phytoreducing agents for the biosynthesis of metallic nanoparticles. Microb Pathogen. 2021. https://doi.org/10.1016/j.micpath.2021.105107.10.1016/j.micpath.2021.105107 ↗
43. Skłodowski K, Chmielewska-Deptuła SJ, Piktel E, Wolak P, Wollny T, Bucki R. Metallic nanosystems in the development of antimicrobial strategies with high antimicrobial activity and high biocompatibility. Int J Mol Sci. 2023. https://doi.org/10.3390/ijms24032104.10.3390/ijms24032104 ↗
44. R. P. Allaker, The use of antimicrobial nanoparticles to control oral infections, chapter, nano-antimicrobials, 2012. ISBN : 978–3–642–24427–8
45. Mohd Yusof H, Mohamad R, Zaidan UH, et al. Microbial synthesis of zinc oxide nanoparticles and their potential application as an antimicrobial agent and a feed supplement in animal industry: a review. J Animal Sci Biotechnol. 2019;10:57. https://doi.org/10.1186/s40104-019-0368-z.10.1186/s40104-019-0368-z ↗
46. de Souza AG, Komatsu LGH, Barbosa RFS, et al. The effect of ZnO nanoparticles as Ag-carrier in PBAT for antimicrobial films. Polym Bull. 2022;79:4031–48. https://doi.org/10.1007/s00289-021-03681-2.10.1007/s00289-021-03681-2 ↗
47. Kaur T, Bala M, Kumar G, et al. Biosynthesis of zinc oxide nanoparticles via endophyte Trichoderma viride and evaluation of their antimicrobial and antioxidant properties. Arch Microbiol. 2022;204:620. https://doi.org/10.1007/s00203-022-03218-9.10.1007/s00203-022-03218-9 ↗
48. Ghaedi M, Yousefi-Nejad M, Safarpoor M, Khafri HZ, Tyagi I, Agarwal S, Gupta VK. Synthesis of CuS nanoparticles and evaluation of its antimicrobial properties in combination with Linumusitatissimum root and shoot extract. Desalin Water Treat. 2016;57(51):24456–66. https://doi.org/10.1080/19443994.2016.1138896.10.1080/19443994.2016.1138896 ↗
49. Alejandra Arévalo-Gallegos J, Garcia-Perez S, Danay Carrillo-Nieves RA, Ramirez-Mendoza HMN, Iqbal & Roberto Parra-Saldívar,. Botryococcusbraunii as a bioreactor for the production of nanoparticles with antimicrobial potentialities. Int J Nanomed. 2018;13:5591–604. https://doi.org/10.2147/IJN.S174205.10.2147/IJN.S174205 ↗
50. Darvish HB, Bahrami A, Jafari SM, Williams L. Micro/nanoencapsulation strategy to improve the efficiency of natural antimicrobials against Listeria monocytogenes in food products. Crit Rev Food Sci Nutr. 2021;61(8):1241–59. https://doi.org/10.1080/10408398.2020.1755950.10.1080/10408398.2020.1755950 ↗
51. Saravanan M, Barabadi H, Vahidi H. Green nanotechnology: isolation of bioactive molecules and modified approach of biosynthesis. In: Biogenic nanoparticles for cancer theranostics 2021 Jan 1 (pp. 101–122). Elsevier. https://doi.org/10.1016/B978-0-12-821467-1.00005-710.1016/B978-0-12-821467-1.00005-7 ↗
52. Nguyen NTT, Nguyen LM, Nguyen TTT, et al. Formation, antimicrobial activity, and biomedical performance of plant-based nanoparticles: a review. Environ Chem Lett. 2022;20:2531–71. https://doi.org/10.1007/s10311-022-01425-w.10.1007/s10311-022-01425-w ↗
53. Pourhajibagher M, Noroozian M, Ahmad Akhoundi MS, et al. Antimicrobial effects and mechanical properties of poly(methyl methacrylate) as an orthodontic acrylic resin containing Curcumin-Nisin-poly(L-lactic acid) nanoparticle: an in vitro study. BMC Oral Health. 2022;22:158. https://doi.org/10.1186/s12903-022-02197-z.10.1186/s12903-022-02197-z ↗
54. Anushikha GKK. Lignin as a UV blocking, antioxidant, and antimicrobial agent for food packaging applications. Biomass Conv Bioref. 2023. https://doi.org/10.1007/s13399-022-03707-3.10.1007/s13399-022-03707-3 ↗
55. Neupane BP, Chaudhary D, Paudel S, Timsina S, Chapagain B, Jamarkattel N, Tiwari BR. Himalayan honey loaded iron oxide nanoparticles: synthesis, characterization and study of antioxidant and antimicrobial activities. Int J Nanomed. 2019;14:3533–41. https://doi.org/10.2147/IJN.S196671.10.2147/IJN.S196671 ↗
56. Akbar S, Tauseef I, Subhan F, Sultana N, Khan I, Ahmed U, Haleem KS. An overview of the plant-mediated synthesis of zinc oxide nanoparticles and their antimicrobial potential. Inorganic Nano-Metal Chem. 2020;50(4):257–71. https://doi.org/10.1080/24701556.2019.1711121.10.1080/24701556.2019.1711121 ↗
57. Qiao Y, Han Y, Guan R, et al. Inorganic hollow mesoporous spheres-based delivery for antimicrobial agents. Front Mater Sci. 2023;17: 230631. https://doi.org/10.1007/s11706-023-0631-2.10.1007/s11706-023-0631-2 ↗
58. Thapa RK, Diep DB, Tønnesen HH. Nanomedicine-based antimicrobial peptide delivery for bacterial infections: recent advances and future prospects. J Pharm Investig. 2021;51:377–98. https://doi.org/10.1007/s40005-021-00525-z.10.1007/s40005-021-00525-z ↗
59. Varier KM, et al. (2019) Nanoparticles: antimicrobial applications and its prospects. In: Naushad M, Rajendran S, Gracia F (eds) Advanced nanostructured materials for environmental remediation. Environmental Chemistry for a Sustainable World, vol 25. Springer, Cham. https://doi.org/10.1007/978-3-030-04477-0_1210.1007/978-3-030-04477-0_12 ↗
60. Cyganowski P, Caban M, Khan MA, et al. The use of cold atmospheric pressure plasma for the synthesis of saccharide-stabilized re nanostructures enabling effective deactivation of nitro-based antimicrobial agents. Plasma Chem Plasma Process. 2023;43:199–224. https://doi.org/10.1007/s11090-022-10285-9.10.1007/s11090-022-10285-9 ↗
61. Akin B, Ozmen MM. Antimicrobial cryogel dressings towards effective wound healing. Prog Biomater. 2022;11:331–46. https://doi.org/10.1007/s40204-022-00202-w.10.1007/s40204-022-00202-w ↗
62. Punjataewakupt A, Napavichayanun S, Aramwit P. The downside of antimicrobial agents for wound healing. Eur J Clin Microbiol Infect Dis. 2019;38:39–54. https://doi.org/10.1007/s10096-018-3393-5.10.1007/s10096-018-3393-5 ↗
63. Shah BA, Yuan B, Yan Y, et al. Boost antimicrobial effect of CTAB-capped NixCu1−xO (0.0 ≤ x ≤ 0.05) nanoparticles by reformed optical and dielectric characters. J Mater Sci. 2021;56:13291–312. https://doi.org/10.1007/s10853-021-06130-7.10.1007/s10853-021-06130-7 ↗
64. Lopes NA, Brandelli A, Nanostructures for delivery of natural antimicrobials in food. Crit Rev Food Sci Nutrit, 2018;58(13), 2202-221210.1080/10408398.2017.1308915 ↗
65. Samadian H, Salami MS, Jaymand M, Azarnezhad A, Najafi M, Barabadi H, Ahmadi A. Genotoxicity assessment of carbon-based nanomaterials; Have their unique physicochemical properties made them double-edged swords? Mutat Res. 2020;1(783): 108296. https://doi.org/10.1016/j.mrrev.2020.108296.10.1016/j.mrrev.2020.108296 ↗
66. SolmazMalekiDizaj SS, AzinJahangiri,. Electrospun nanofibers as versatile platform in antimicrobial delivery: current state and perspectives. Pharm Dev Technol. 2019;24(10):1187–99. https://doi.org/10.1080/10837450.2019.1656238.10.1080/10837450.2019.1656238 ↗
67. Cacciatore FA, Adriano Brandelli&Patrícia da Silva Malheiros,. Combining natural antimicrobials and nanotechnology for disinfecting food surfaces and control microbial biofilm formation. Crit Rev Food Sci Nutr. 2021;61(22):3771–82. https://doi.org/10.1080/10408398.2020.1806782.10.1080/10408398.2020.1806782 ↗
68. Tian Yu, Cai R, Yue T, Gao Z, Yuan Y, Wang Z. Application of nanostructures as antimicrobials in the control of foodborne pathogen. Crit Rev Food Sci Nutr. 2022;62(14):3951–68. https://doi.org/10.1080/10408398.2021.1871586.10.1080/10408398.2021.1871586 ↗
69. Staroń A, Długosz O. Antimicrobial properties of nanoparticles in the context of advantages and potential risks of their use. J Environ Sci Health Part A. 2021;56(6):680–93. https://doi.org/10.1080/10934529.2021.1917936.10.1080/10934529.2021.1917936 ↗
70. Rosli NA, Teow YeitHaan, Mahmoudi E. Current approaches for the exploration of antimicrobial activities of nanoparticles. Sci Technol Adv Mater. 2021;22(1):885–907. https://doi.org/10.1080/14686996.2021.1978801.10.1080/14686996.2021.1978801 ↗
71. Huang T, Li X, Maier M, O’Brien-Simpson NM, Heath DE, O’Connor AJ. Using inorganic nanoparticles to fight fungal infections in the antimicrobial resistant era. Acta Biomater. 2023;158:56–79. https://doi.org/10.1016/j.actbio.2023.01.019.10.1016/j.actbio.2023.01.019 ↗
72. Fabio GB, Martin BA, Dalmolin LF, Lopez RFV. Antimicrobial photodynamic therapy and the advances impacted by the association with nanoparticles. J Drug Deliv Sci Technol. 2023. https://doi.org/10.1016/j.jddst.2022.104147.10.1016/j.jddst.2022.104147 ↗
73. Hamida RS, Ali MA, Alfassam HE, Momenah MA, Alkhateeb MA, Bin-Meferij MM. One-step phytofabrication method of silver and gold nanoparticles using haloxylonsalicornicum for anticancer, antimicrobial, and antioxidant activities. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15020529.10.3390/pharmaceutics15020529 ↗
74. Moreno Ruiz YP, de Almeida Campos LA, Alves Agreles MA, Galembeck A, Macário Ferro Cavalcanti I. Advanced hydrogels combined with silver and gold nanoparticles against antimicrobial resistance. Antibiotics. 2023. https://doi.org/10.3390/antibiotics12010104.10.3390/antibiotics12010104 ↗
75. Chauhan V, Dhiman VK, Mahajan G, Pandey A, Kanwar SS. Synthesis and characterization of silver nanoparticles developed using a novel lipopeptide(s) biosurfactant and evaluating its antimicrobial and cytotoxic efficacy. Process Biochem. 2023;124:51–62. https://doi.org/10.1016/j.procbio.2022.11.002.10.1016/j.procbio.2022.11.002 ↗
76. Das RK, Pachapur VL, Lonappan L, et al. Biological synthesis of metallic nanoparticles: plants, animals and microbial aspects. Nanotechnol Environ Eng. 2017;2:18. https://doi.org/10.1007/s41204-017-0029-4.10.1007/s41204-017-0029-4 ↗
77. AbdEl-Aziz NK, Ammar AM, El-Naenaeey EYM, et al. Antimicrobial and antibiofilm potentials of cinnamon oil and silver nanoparticles against Streptococcus agalactiae isolated from bovine mastitis: new avenues for countering resistance. BMC Vet Res. 2021;17:136. https://doi.org/10.1186/s12917-021-02842-9.10.1186/s12917-021-02842-9 ↗
78. Thammawithan S, Talodthaisong C, Srichaiyapol O, et al. Andrographolide stabilized-silver nanoparticles overcome ceftazidime-resistant Burkholderiapseudomallei: study of antimicrobial activity and mode of action. Sci Rep. 2022;12:10701. https://doi.org/10.1038/s41598-022-14550-x.10.1038/s41598-022-14550-x ↗
79. Aboelmagd LA, Tolba E, AbdelAziz ZA. Chitosan–organosilica hybrid decorated with silver nanoparticles for antimicrobial wearable cotton fabrics. Polym Bull. 2023;80:4229–43. https://doi.org/10.1007/s00289-022-04250-x.10.1007/s00289-022-04250-x ↗
80. Elemike EE, Onwudiwe DC, Fayemi OE, et al. Biosynthesis, electrochemical, antimicrobial and antioxidant studies of silver nanoparticles mediated by talinum triangulare aqueous leaf extract. J Clust Sci. 2017;28:309–30. https://doi.org/10.1007/s10876-016-1087-7.10.1007/s10876-016-1087-7 ↗
81. Devi LS, Joshi SR. Evaluation of the antimicrobial potency of silver nanoparticles biosynthesized by using an endophytic fungus, Cryptosporiopsisericae PS4. J Microbiol. 2014;52:667–74. https://doi.org/10.1007/s12275-014-4113-1.10.1007/s12275-014-4113-1 ↗
82. Irfan M, Perero S, Miola M, et al. Antimicrobial functionalization of cotton fabric with silver nanoclusters/silica composite coating via RF co-sputtering technique. Cellulose. 2017;24:2331–45. https://doi.org/10.1007/s10570-017-1232-y.10.1007/s10570-017-1232-y ↗
83. Xu X, Zhou M. Antimicrobial gelatin nanofibers containing silver nanoparticles. Fibers Polym. 2008;9:685–90. https://doi.org/10.1007/s12221-008-0108-z.10.1007/s12221-008-0108-z ↗
84. Ahmad N, Muhammad J, Khan K, et al. Silver and gold nanoparticles induced differential antimicrobial potential in calli cultures of Prunella vulgaris. BMC Chem. 2022;16:20. https://doi.org/10.1186/s13065-022-00816-y.10.1186/s13065-022-00816-y ↗
85. Das D, Ghosh R, Mandal P. Biogenic synthesis of silver nanoparticles using S1 genotype of Morus alba leaf extract: characterization, antimicrobial and antioxidant potential assessment. SN Appl Sci. 2019;1:498. https://doi.org/10.1007/s42452-019-0527-z.10.1007/s42452-019-0527-z ↗
86. Mikiciuk J, EwaMikiciuk AW, Szterk A. Antimicrobial potential of commercial silver nanoparticles and the characterization of their physical properties toward probiotic bacteria isolated from fermented milk products. J Environ Sci Health B. 2016;51(4):222–9. https://doi.org/10.1080/03601234.2015.1120614.10.1080/03601234.2015.1120614 ↗
87. Thangapushbam V, Muthu K. Biosynthesis of silver nanoparticles using Martynia annua and its antimicrobial and cytotoxic activities. Mater Technol. 2022;37(14):3174–83. https://doi.org/10.1080/10667857.2022.2135475.10.1080/10667857.2022.2135475 ↗
88. Ghosh S, Patil S, Ahire M, Kitture R, Kale S, Pardesi K, Cameotra SS, Bellare J, Dhavale DD, Amit Jabgunde&Balu A Chopade,. Synthesis of silver nanoparticles using Dioscoreabulbifera tuber extract and evaluation of its synergistic potential in combination with antimicrobial agents. Int J Nanomed. 2012;7:483–96. https://doi.org/10.2147/IJN.S24793.10.2147/IJN.S24793 ↗
89. Lomelí-Marroquín D, Cruz DM, Nieto-Argüello A, Crua AV, Chen J, Torres-Castro A, Webster TJ, Cholula-Díaz JL. Starch-mediated synthesis of mono- and bimetallic silver/gold nanoparticles as antimicrobial and anticancer agents. Int J Nanomed. 2019;14:2171–90. https://doi.org/10.2147/IJN.S192757.10.2147/IJN.S192757 ↗
90. Hembram KC, Kumar R, Kandha L, Parhi PK, Kundu CN, Bindhani BK. Therapeutic prospective of plant-induced silver nanoparticles: application as antimicrobial and anticancer agent. Artif Cells Nanomed Biotechnol. 2018;46(sup3):38–51. https://doi.org/10.1080/21691401.2018.1489262.10.1080/21691401.2018.1489262 ↗
91. Saravanan M, Barabadi H, Vahidi H, Webster TJ, Medina-Cruz D, Mostafavi E, Vernet-Crua A, Cholula-Diaz JL, Periakaruppan P. Emerging theranostic silver and gold nanobiomaterials for breast cancer: present status and future prospects. Handb Nanobiomater Therapeut Diagnost Appl. 2021;1:439–56. https://doi.org/10.1016/B978-0-12-821013-0.00004-0.10.1016/B978-0-12-821013-0.00004-0 ↗
92. Mahmoud W, Ahmed M, Elazzazy&Enas N. Danial,. In vitro evaluation of antioxidant, biochemical and antimicrobial properties of biosynthesized silver nanoparticles against multidrug-resistant bacterial pathogens. Biotechnol Biotechnol Equip. 2017;31(2):373–9. https://doi.org/10.1080/13102818.2017.1282836.10.1080/13102818.2017.1282836 ↗
93. Chung IM, Park I, Seung-Hyun K, et al. Plant-mediated synthesis of silver nanoparticles: their characteristic properties and therapeutic applications. Nanoscale Res Lett. 2016;11:40. https://doi.org/10.1186/s11671-016-1257-4.10.1186/s11671-016-1257-4 ↗
94. Khan MA, Ahmad S, Batool SA, Noor S, Rashid S. Biosynthesis of zinc oxide nanoparticles by using Lallemantiaroyleana seed extract, characterization and evaluation of their hemolytic, and catalytic degradative properties. Inorganic Nano-Metal Chem. 2023. https://doi.org/10.1080/24701556.2023.2172043.10.1080/24701556.2023.2172043 ↗
95. Burange PJ, Tawar MG, Bairagi RA, et al. Synthesis of silver nanoparticles by using Aloe vera and Thuja orientalis leaves extract and their biological activity: a comprehensive review. Bull Natl Res Cent. 2021;45:181. https://doi.org/10.1186/s42269-021-00639-2.10.1186/s42269-021-00639-2 ↗
96. Joshi N, Pathak A, Anupam R, et al. A rapid and efficient biosynthesis of metallic nanoparticles using aqueous extract of chia (Salvia hispanica L) seeds. BioNanoSci. 2019;9:893–902. https://doi.org/10.1007/s12668-019-00672-6.10.1007/s12668-019-00672-6 ↗
97. Agnihotri S, Sillu D, Sharma G, et al. Photocatalytic and antibacterial potential of silver nanoparticles derived from pineapple waste: process optimization and modeling kinetics for dye removal. Appl Nanosci. 2018;8:2077–92. https://doi.org/10.1007/s13204-018-0883-9.10.1007/s13204-018-0883-9 ↗
98. Vijayakumar S, Divya M, Vaseeharan B, et al. Biological compound capping of silver nanoparticle with the seed extracts of blackcumin (Nigella sativa): a potential antibacterial, antidiabetic, anti-inflammatory, and antioxidant. J InorgOrganometPolym. 2021;31:624–35. https://doi.org/10.1007/s10904-020-01713-4.10.1007/s10904-020-01713-4 ↗
99. Fatima F, Wahid I. Eco-friendly synthesis of silver and copper nanoparticles by Shizophyllum commune fungus and its biomedical applications. Int J Environ Sci Technol. 2022;19:7915–26. https://doi.org/10.1007/s13762-021-03517-6.10.1007/s13762-021-03517-6 ↗
100. Saratale RG, Shin HS, Kumar G, et al. Exploiting fruit byproducts for eco-friendly nanosynthesis: Citrus × clementina peel extract mediated fabrication of silver nanoparticles with high efficacy against microbial pathogens and rat glial tumor C6 cells. Environ Sci Pollut Res. 2018;25:10250–63. https://doi.org/10.1007/s11356-017-8724-z.10.1007/s11356-017-8724-z ↗